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Bioactive natural compounds for the fight against cancer

New synthesis route manages without toxic and expensive oxidizing agent and at the same time proves to be much more efficient

29-Jun-2020

Phytoalexins are bioactive phytochemicals that have attracted much attention in recent years due to their health-promoting effects in humans and their vital role in plant health. Chemists at TU Dresden have now developed a new and very efficient synthesis for these substances. With the new ...

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How do our cells respond to stress?

Molecular biologists reverse-engineer a complex cellular structure that is associated with neurodegenerative diseases such as ALS

23-Apr-2020

Cells are often exposed to stressful conditions that can be life threatening, such as high temperatures or toxins. Fortunately, our cells are masters of stress management with a powerful response program: they cease to grow, produce stress-protective factors, and form large structures, which are ...

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Blood stem cells boost immunity by keeping a record of previous infections

A newly discovered memory in our bones

17-Mar-2020

A Franco-German research team led by Prof. Michael Sieweke, from the Center for Regenerative Therapies TU Dresden (CRTD) and the Center of Immunology of Marseille Luminy (CNRS, INSERM, Aix-Marseille University), today uncovered a surprising property of blood stem cells: not only do they ensure ...

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Biologists make living sperm glow

16-Jan-2020

By applying a novel method, biologists at TU Dresden have successfully analysed the metabolism of intact tissues of the fruit fly using a label-free microscopy technique. They used the natural fluorescence of certain metabolic molecules and found that sperm, compared to other tissues, are highly ...

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What happens to deferred intentions in the brain?

14-Jan-2020

Placing a checkmark on the to-do list is an extremely liberating feeling for many eager list lovers, especially when the task has been postponed for a long time. But what happens in our brain when we have completed a postponed task? Will it be deactivated? If so, how? A team of scientists from ...

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Rejuvenating the brain

More stem cells improve learning and memory of old mice

13-Jan-2020

We all will experience it at some point, unfortunately: The older we get the more our brains will find it difficult to learn and remember new things. What the reasons underlying these impairments are is yet unclear but scientists at the Center for Regenerative Therapies of TU Dresden (CRTD) ...

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"Census" in the zebrafish's brain

Scientists explore newborn, regenerated neurons

09-Jan-2020

The zebrafish is a master of regeneration: If brain cells are lost due to injury or disease, it can simply reproduce them - contrary to humans where this only happens in the fetal stage. However, the zebrafish is evolutionarily related to humans and, thus, possesses the same brain cell types as ...

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Fast and cheap low-tech method to test for the presence of any DNA sequence

10-Dec-2019

The student project DipGene developed a new methodology that makes genetic testing as easy as a pH-test. With their simple, cheap and low-tech method to test for the presence of any DNA sequence, they won a prestigious Gold Medal. A student team of the TU Dresden successfully showcased their ...

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Fungus produces active agent in a medicinal herb

Researchers discover that a fungus in Tatarinow’s aster produces bioactive agents

09-Dec-2019

Tatarinow's aster is used in traditional Chinese medicine to treat a number of ailments; the plant contains an active ingredient known as astin – and it is this agent which cancer researchers are now investigating. However, the plant does not produce the astins itself, as was assumed for a long ...

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Biologists examine sperm quality on the basis of their metabolism

02-Dec-2019

Every tenth couple worldwide is affected by infertility. The reasons for this are manifold, but mostly well researched. Nevertheless, about fifteen percent of cases remain unexplained. A team of biologists at TU Dresden has now gained new insights into the metabolic properties that make up a good ...

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