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5 Current news of Fondazione IFOM

Like flocks of birds: How cancer cells develop metastases

05-Feb-2015 - They migrate in groups of at least 23 members, moving in an autonomous and seemingly random, but perfectly coordinated and compact way. A group leader indicates the movement strategies and migration route. To ensure the effectiveness of migration, the role of leader, more exposed to environmental ...

B cells bioinformatics cancer +5

Between ALS and cancer: perhaps a link in a protein

19-Nov-2012 - Senataxin, a protein involved in two major hereditary neurodegenerative diseases, including a form of ALS, is now back in the spotlight for its novel role as guardian of genome stability, revealing an interesting parallel between tumours and neurodegenerative diseases. The study, conducted ...

amyotrophic lateral sclerosis ataxia DNA damage +2
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DNA: in telomeres lesions of time are inevitable

21-Mar-2012 - A study conducted at IFOM in Milan has revealed that there are regions of the genome that are completely undefended. They are the telomeres, or extremities of the chromosomes that, by shortening with each cellular proliferation cycle, mark the inexorable passage of time and lead to cellular ...

chromosomes DNA damage genomes +2

Chromosomal acrobatics help protect against cancer

07-Sep-2009 - Scientists at IFOM have used an experimental approach to create a three-dimensional view of the process that helps to protect DNA stability and defend us against spontaneous cancer-causing mutations. The discovery, published in Cell advances theunderstanding of the molecular basis of cancer and ...

biotechnology cell division DNA damage +7

Zooming in on genome breakages could reveal hidden secrets of cancer

15-Apr-2009 - Scientists at IFOM in Milan have uncovered the mechanisms that cause tumours to develop in patients suffering from Ataxia-Telangiectasia (AT) and Ataxia-Telangiectasia Like Disorder (ATLD): rare hereditary diseases that predispose afflicted individuals to cancer. The study opens new avenues for ...

ataxia biotechnology breast cancer +15