Start-up Lifespin launches therapeutic drug monitoring of anti-infectives

An important step towards integrating precision medicine and antibiotic resistance control

07-Dec-2023
Computer-generated image

By accurately measuring antibiotics in patient blood, Lifespin's TDM of anti-infectives enables physicians to adjust treatments more effectively and address the challenge of variable patient responses to medication. This approach is crucial to prevent therapeutic failures and reduce the risk of developing antibiotic-resistant strains (symbolic image).

Lifespin GmbH, an emerging company in the field of precision health information, introduces its Therapeutic Drug Monitoring (TDM) of anti-infectives. This Laboratory Development Test (LDT) represents a significant advance in the field of personalized medicine by enabling individualized approaches to antibiotic therapy in the treatment of sepsis and respiratory infections such as pneumonia.

To meet the anticipated demand for this new approach to one of the most pressing challenges in modern medicine, Lifespin is expanding the capabilities of its TDM of anti-infectives beyond its own diagnostic laboratories to licensed laboratories worldwide. This expansion is made possible by Lifespin's plug-and-play cloud system, which allows licensed laboratories to use Lifespin's proprietary algorithm. Laboratories with suitable hardware can now measure patient blood samples locally and use Lifespin's software via the cloud for analysis. The TDM product, which uses NMR spectroscopy technology as a measurement tool, is designed to work seamlessly with Lifespin's software. This integration ensures the precise determination of drug concentrations in human serum samples, which is essential for selecting the most effective treatments. By accurately measuring antibiotics in patient blood, Lifespin's TDM of anti-infectives enables physicians to customize treatments more effectively and address the challenge of variable patient responses to drugs. This approach is crucial to prevent therapeutic failures and reduce the risk of developing antibiotic-resistant strains. Currently, the TDM product tests for all common antibiotics/antifungals, including cefotiam (RUO), ceftazidime, cefuroxime, fosfomycin, ceftriaxone, flucloxacillin, piperacillin, fluconazole and flucytosine (RUO).

"The launch of our drug monitoring for anti-infectives marks a significant milestone in our mission to transform the landscape of precision medicine," said Dr. Ali Tinazli, CEO of Lifespin. "In response to market demand for improved antibiotic use, we have made this breakthrough technology available globally through our cloud-based system. This enables us to offer personalized treatment options to laboratories worldwide. Looking ahead, I am optimistic about our upcoming product launches in 2024, which will further expand our capabilities in precision medicine and significantly improve health outcomes."

Dr. Thorsten Zacher, Head of Business Development & Sales at Lifespin, adds: "The flexible, automated Lifespin configuration enables us to provide same-day drug concentrations to local intensivists and pharmacists, as well as being a scalable high-throughput partner for clinical trials."

Note: This article has been translated using a computer system without human intervention. LUMITOS offers these automatic translations to present a wider range of current news. Since this article has been translated with automatic translation, it is possible that it contains errors in vocabulary, syntax or grammar. The original article in German can be found here.

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