Long term loss of smell and taste for 27 million covid patients worldwide
Women were less likely to recover their sense of smell and taste
Photo by Daniel Apodaca on Unsplash
The loss of taste and smell are common reported symptoms in COVID-19 patients, with up to 50% of patients globally experiencing them, but little is known about their clinical course or how many patients develop persistent dysfunction.
There are more than 550 million confirmed COVID-19 cases to date (as of July 2022). Of which, about 15 million and 12 million patients may experience long term smell and taste dysfunction respectively, according to the study.
The loss of smell and taste can have an impact on quality of life and general health and this could contribute to the rising burden of long COVID, a long-term side effect from their infection.
Based on 18 observational studies involving 3,699 patients from 12 countries, the research team utilised a mathematical technique known as cure modelling to estimate self -reported rates of smell and taste recovery and identify key factors associated with the duration and likelihood of recovery. They found that 5.6% and 4.4% of patients might develop long lasting self-reported smell and taste dysfunction post-covid-19, respectively – about 15 million and 12 million patients worldwide as of July 2022. At 30 days after initial infection, only 74% and 79% of patients had their sense of smell and taste restored respectively.
Women were less likely to recover their sense of smell and taste, and patients with greater initial severity of dysfunction and those with nasal congestion were less likely to recover their sense of smell.
While most patients are expected to recover their sense of smell or taste within the first three months, a group of patients might develop long lasting dysfunction that requires timely identification, personalised treatment, and long-term follow-up.
These findings are likely to be of substantial relevance to general doctors and otolaryngologists in the counselling of patients with smell and taste disorders post-COVID-19, the team concluded.
“We hope that the results of this study will draw the attention of the medical fraternity worldwide to the long-term issues associated with taste and smell loss. There are studies that point to poorer quality of life, depression and higher mortality in patients with poorer smell function even before this pandemic. Healthcare providers around the world should be cognizant of this given the huge number of affected individuals that need support and help,” said Associate Professor Toh Song Tar, Head, Department of Otorhinolaryngology–Head & Neck Surgery, Singapore General Hospital (SGH).
Other news from the department science
Revolutionary cell therapy: rebooting the immune system stops autoimmune diseases
Single infusion of CAR-T cells replaces immunosuppressive drugs
Cracking the Code of Neurodegeneration: New Model Identifies Potential Therapeutic Target
Novel neural cell culture model developed
IQ does not remain the same throughout life
A meta-study shows that an intelligence quotient measured once is not necessarily meaningful later on
New mechanism for regulating cell division in the bacterial pathogen Klebsiella uncovered
Small ribonucleic acid with a big impact
More brain than trait: Decoding the neural pathways of curiosity
Discovery sheds new light on the biological basis of human curiosity and could have far-reaching implications for the understanding and treatment of diseases
What Our Genetic Information Tells Us About Type 2 Diabetes Risk and Complications
Largest Study on Genetic Risk for Diabetes Now Published
Study Proposes Framework to Standardize Biomarkers of Aging and Accelerate Clinical Use
Improving the life expectancy and health of the population
Researchers succeeded in biomanufacturing using chemically synthesized sugar for the first time in the world
Biomanufacturing using chemically synthesized sugars enables sustainable supply of sugar without competing with food
What can bulls tell us about men?
Towards a better understanding: Which genes and mechanisms control male fertility?
µkiss-and-tell: A new method for precision delivery of nanoparticles and small molecules to individual cells
"Like a paintbrush", easy and cost-effective to use
How COVID-19 affects the brain
Neurological symptoms apparently not a result of SARS-CoV-2 infection of the brain
Microscopy: Overcoming the traditional resolution limit for the fast co-tracking of molecules
Researchers have developed an innovative method to simultaneously track rapid dynamic processes of multiple molecules at the molecular scale
Shredding to plan – protein recycling for immune defense
“If we know how the proteasome generates immunopeptides, we can predict peptide splicing. In future, these predictions could, in turn, help develop novel vaccines against cancer or infectious diseases”
New nanosensors make diagnostic procedures more sensitive
The nanosensors can be used to track reactions with invisible light, saving materials and time
Most read news
mRNA therapeutic successfully combats ovarian cancer
The mRNA therapeutic successfully combated cancerous cells and tumors in vitro as well as metastases in mice
The secret of whales: How giant whales defy cancer
Study of gigantism in whales provides clues to genomic mechanism involved in tumor suppression
Microbe of the Year 2023: Bacillus subtilis – for health and technology
Already, Bacillus subtilis is indispensable in many industries, and many more innovations are expected
Making Ends Meet: Researchers Find That a Protein Superglue is Crucial for DNA Damage Repair
New Understanding for Cancer Treatments
A standard blood test can predict a heart attack
Using the results of a standard blood test and an online tool, you can find out if you are at increased risk of having a heart attack within six months
Learning from Nature: How a fungus makes a hard job easier
Researchers analyze a fungal biosynthetic pathway and discover a capable enzyme
Innovative microscopy technique reveals secrets of lipid synthesis inside cells
Two-color infrared photothermal microscopy (2C-IPM) opens new avenues for long-term study of lipid metabolism in living cells
Artificial cartilage with the help of 3D printing
New approach to producing artificial tissue works with cells in microstructures from the 3D printer
Destroying Tumor Cells with Calcium
Activating calcium channels leads to a deadly influx of calcium ions into tumor cells
New agent blocks stress response
In the future, this could enable stress-related conditions such as chronic depression to be treated much more specifically and with fewer side effects
More news from our other portals
Mystery of Novel Clove-Like Off-Flavor in Orange Juice Solved
Tracking down off-flavours using techniques such as gas chromatography-olfactometry and aroma extract dilution analysis
Planned EU legislation on packaging threatens popular seasonal confectionery
Federal Association of the German Confectionery Industry fears the end of chocolate Easter bunnies & Co.
Green steel from toxic red mud
An economical process with green hydrogen can be used to extract CO2-free iron from the red mud generated in aluminium production
Chemists are on the hunt for the other 99 percent
New mass spectrometry combo offers promise for tapping nature’s unknown chemical universe
Battery start-up is developing safe, long-lasting thin-film solid-state batteries that can be charged and discharged in one minute
BTRY raises CHF 900,000 in pre-seed funding for the development of an innovative solid-state battery
BASF and Envision Energy enter a collaboration to drive sustainable energy solutions
Collaboration to accelerate conversion of green hydrogen and CO2 to e-methanol
GPT-3 for chemical research
Researchers develop fast and user-friendly language model for chemical tasks
Eckes-Granini further expands important out-of-home business segment
Market share gains and double-digit sales growth in 2023
Revolutionizing batteries: Coffee grounds power high-performance sodium-ion anodes
Using coffee waste as a precursor material for hard carbon synthesis
Microgreens made to order
Italian scientists have tailored iodine and potassium content of radishes, peas, rocket and chard
Greetings from the island of enhanced stability: The quest for the limit of the periodic table
A fresh view on new superheavy elements
World first: The first CO2-negative biofuel comes from Germany
Start-up Carbon Farming Germany revolutionizes fuel production with BeyondZero
Detect 'forever chemicals' in under 3 minutes
New lab-based method to detect traces of PFAS from food packaging material, water and soil samples