19-Aug-2020 - Evotec SE

Evotec and Novo Nordisk form alliance to develop novel therapies for kidney diseases

Milestone potential of more than € 150 m per product

Evotec SE and Novo Nordisk announced a strategic collaboration on the discovery and development of innovative therapeutics for patients with chronic kidney disease.

Evotec and Novo Nordisk will jointly identify and develop novel targets based on comprehensive medical and molecular data sets of thousands of chronic kidney disease patients. The collaboration intends to pursue the most relevant human disease biology in a therapeutic modality-agnostic approach to develop first-in-class therapeutics for patients suffering from CKD.

Dr Cord Dohrmann, Chief Scientific Officer of Evotec, commented: “We are proud to collaborate with Novo Nordisk in this field of very high unmet medical need. Based on a better understanding of disease-driving molecular mechanisms we aim to develop disease-modifying therapies, which are urgently needed.”

Dr Marcus Schindler, SVP of Global Drug Discovery at Novo Nordisk, commented: “Building on our excellent existing relationship with Evotec, we are very excited to embark on this new collaboration in chronic kidney disease (“CKD”). Collaborating on cutting-edge science, with a human data-centric approach, gives us a unique opportunity to discover novel treatments for the benefit of people living with CKD.”

Dr Karin Conde-Knape, CVP Global Diabetes, Cardio-renal and Translational Research at Novo Nordisk, commented: “Building on adjacencies within cardio-renal and metabolism, this collaboration will allow us to strengthen our efforts within kidney disease on the basis of human relevant biology and strong knowhow and capabilities in collaboration with Evotec.”

Under the terms of the agreement, Evotec and Novo Nordisk will share responsibilities during drug discovery and pre-clinical development. Novo Nordisk will be responsible for the clinical development and commercialisation of the products. Evotec will receive an undisclosed upfront payment, research funding and milestone potential of more than € 150 m per product as well as tiered royalties on net sales.

Facts, background information, dossiers
More about Evotec
  • News

    Evotec and Secarna form strategic partnership in the field of antisense therapy

    Evotec SE and Secarna Pharmaceuticals GmbH & Co. KG (Secarna) announced a strategic partnership in the field of antisense oligonucleotide (“ASO”)-based therapeutics. Antisense therapy is an innovative, clinically and commercially validated, highly-targeted pharmacological approach which int ... more

    Evotec to produce monoclonal antibody products against COVID-19 for the Department of Defense

    Evotec SE announced that the U.S. Department of Defense (“DOD”) awarded its Seattle-based subsidiary, Just – Evotec Biologics, Inc. a contract valued up to $ 18.2 m to develop and manufacture monoclonal antibodies (“mAbs”) for treatment and/or prevention of COVID-19. The goal of this progra ... more

    Evotec enters partnership with Vienna start-up

    Evotec SE announced that the Company has entered into a comprehensive partnership with the recently established QUANTRO Therapeutics GmbH, a research-based biotech company based in Vienna, Austria, that strives to discover and develop novel therapeutics interfering with disease-causing tran ... more

  • Companies

    Evotec SE

    Evotec is a leading drug discovery alliance and development partnership company focused on rapidly progressing innovative product approaches. The Company operates worldwide providing the highest quality stand-alone and integrated drug discovery solutions, covering all activities from target ... more

    Evotec Neurosciences GmbH

    Evotec is a leader in the discovery and development of novel small molecule drugs. The Company has established a powerful platform that is applicable to targets across all therapeutic areas and has specific expertise in the area of Central Nervous System (CNS) related diseases where it is b ... more

More about Novo Nordisk
  • News

    Evotec and Novo Nordisk form research alliance in diabetes and obesity

    Evotec AG announced a strategic alliance with Novo Nordisk to discover and develop novel small molecule therapies to treat patients suffering from diabetes and obesity as well as co morbidities such as nonalcoholic steatohepatitis (“NASH”), cardiovascular diseases, and diabetic kidney disea ... more

    Novo Nordisk acquires Bristol based biopharmaceutical start-up

    Ziylo and Novo Nordisk A/S today announced that Novo Nordisk has acquired all of the shares of Ziylo, a University of Bristol spin-out company based at Unit DX science incubator in Bristol, UK. Ziylo has been pioneering the use of its platform technology - synthetic glucose binding molecule ... more

    Novo Nordisk completes divestment of ZymoGenetics, Inc.

    Bristol-Myers Squibb Company and ZymoGenetics, Inc. have signed a definitive agreement providing for the acquisition of ZymoGenetics by Bristol-Myers Squibb for USD 9.75 per share in cash. Novo Nordisk has been a shareholder of ZymoGenetics since 1988 and at the time of the transaction, Nov ... more

  • Companies

    Novo Nordisk A/S

    more

    Novo Nordisk Pharma GmbH

    Novo Nordisk is a global company in the health sector and has been leading the way in diabetes care for over 90 years. We also use this many years of experience and expertise to help those affected in the treatment of other chronic diseases: hemophilia, growth disorders and obesity. more

    Novo Nordisk Pharma S.A.

    Novo Nordisk is a global health care company and more than 90 years of innovation and leadership in diabetes. The company also holds leadership positions in the care of hemophilia and growth disorders. more