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Pyrovalerone



Pyrovalerone
Systematic (IUPAC) name
1-(4-methylphenyl)-2-(1-pyrrolidinyl)pentan-1-one
Identifiers
CAS number 3563-49-3
ATC code  ?
PubChem 14373
Chemical data
Formula C16H23NO 
Mol. mass 245.36 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Pyrovalerone (Centroton, Thymergix) is a stimulant drug developed in the late 1960s and used in France and some other European countries. It is sometimes prescribed for treating chronic fatigue and lethargy[1] or as an appetite suppresant, though it is used infrequently due to problems with abuse and dependence. [2] Side effects of pyrovalerone include loss of appetite, anxiety, insomnia, and tremor. Withdrawal syndrome following abuse causes depression. [3] Pyrovalerone is a Schedule 5 drug in the USA. It is closely related to some other stimulant drugs such as prolintane and MDPV.

Additional recommended knowledge


CAS# 1147-62-2 (pyrovalerone hydrochloride); 3563-49-3 (pyrovalerone freebase)

References

  1. ^ Gardos G, Cole JO. Evaluation of pyrovalerone in chronically fatigued volunteers. Current Therapeutic Research, Clinical and Experimental. 1971 Oct;13(10):631-5.
  2. ^ Deniker P, Loo H, Cuche H, Roux JM. Abuse of pyrovalerone by drug addicts. Annales Medico-Psychologiques (Paris) 1975 Nov;2(4):745-8.
  3. ^ http://www.biam2.org/www/Etr8623.html
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Pyrovalerone". A list of authors is available in Wikipedia.
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