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Membranoproliferative glomerulonephritis or MPGN is a type of glomerulonephritis caused by immune complexes depositing in the kidney glomerular mesangium and basement membrane (GBM), activating complement and damaging the glomeruli. The GBM is rebuilt ontop of the deposits, causing a "tram-tracking" appearance under the microscope.
Additional recommended knowledge
There are three types of MPGN.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Membranoproliferative_glomerulonephritis". A list of authors is available in Wikipedia.|