FightAIDS@Home

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FightAIDS@Home ("Fight AIDS at home") is a distributed computing project for internet-connected home computers, operated by the Olson Laboratory at The Scripps Research Institute. It aims to use biomedical software simulation techniques to search for ways to cure or prevent the spread of AIDS and HIV.

It was originally implemented using a distributed computing software infrastructure provided by Entropia. However, since May 2003 FightAIDS@Home has not been associated with Entropia,^[1] and on November 21, 2005 the project moved to World Community Grid and the Entropia software was abandoned.^[2]

FightAIDS@Home makes use of the AutoDock UD agent software, which tests how well a particular molecule binds to the HIV-1 protease. The minimum system requirements to run FightAIDS@home are:^[3]

Scripps Research Institute published its first peer-reviewed scientific paper about the results of FightAIDS@Home on April 21, 2007.^[4] This paper explains that the results up to that point will primarily be used to improve the efficiency of future FightAIDS@Home calculations.^[5]

Publications

Chang, Max W.; Lindstrom, William & Olson, Arthur J. et al., " ", J. Chem. Inf. Model. 47 (3): 1258 - 1262, doi:10.1021/ci700044s,

See also

• List of distributed computing projects

References

1. ^ Worthy Cause: Fight AIDS At Home Computer Project. FuturePundit (2003-12-01). Retrieved on 2007-08-08.
2. ^ FightAIDS@Home. The Scripps Research Institute. Retrieved on 2007-08-08.
3. ^ System Requirements. Help. World Community Grid. Retrieved on 2007-08-08.
4. ^ Chang, Max W.; William Lindstrom, Arthur J. Olson, and Richard K. Belew (2007-04-21). Analysis of HIV Wild-Type and Mutant Structures via in Silico Docking against Diverse Ligand Libraries. J. Chem. Inf. Model. American Chemical Society. DOI:10.1021/ci700044s. Retrieved on 2007-07-30.
5. ^ FightAIDS@Home News Volume 3. The Scripps Research Institute (2007-05-10). Retrieved on 2007-07-30.