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The BMPR1B receptor plays a role in the formation of middle and proximal phalanges  In the chick embryo, it has been shown that BMPR1B is found in precartilaginous condensations. BMPR1B is the major transducer of signals in these condensations as demonstrated in experiments using constitutively active BMPR1B receptors. BMPR1B is a more effective trasducer of GDF5 than BMPR1A. Unlike BMPR1A null mice, which die at an early embryonic stage, BMPR1B null mice are viable.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "BMPR1B". A list of authors is available in Wikipedia.|