How excessive fat tissue affects our blood vessels

New insights into vascular health in obesity

30-Jun-2025 - Obesity plays a crucial role in how severely blood vessels are damaged – and this depends on where excessive fat accumulates in the body. This is the finding of a research team from the German Centre for Cardiovascular Research (DZHK) and the University Medical Center Göttingen (UMG), working ...

How fructose increases the risk of inflammation

Even short-term high fructose consumption influences the immune system

25-Jun-2025 - Despite medical advances, infectious diseases caused by bacteria and viruses are still among the most common causes of death worldwide. What role could fructose play in such diseases? A research group led by Ina Bergheim from the Department of Nutritional Sciences at the University of Vienna has ...

Severe Polyneuritis Successfully Treated with CAR T-Cell Therapy

"We are starting a new chapter in the treatment of severe autoimmune diseases"

20-Jun-2025 - A team of physicians from Bochum are the first to successfully use CAR T-cell therapy to treat two patients with a rare autoimmune disease of the peripheral nervous system. This treatment modifies endogenous immune cells such that they can specifically target and eliminate B lymphocytes, which ...

Sniffing out hunger: a nose-to-brain connection linked to appetite

Nerve cells with a direct connection from the olfactory bulb trigger a feeling of fullness

18-Jun-2025 - No more hunger after cooking? A newly identified network of nerve cells is responsible, a research group at the Max Planck Institute for Metabolism Research has discovered in mice. They discovered a direct connection from the nose to a group of nerve cells in the brain that are activated by the ...

Tracking immune cells inside the body

New method for labeling T cells in immunotherapy

17-Jun-2025 - In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets. Researchers at the Technical University of Munich (TUM) have developed a method for tracking these cells in the body. This new approach could deepen our understanding of cellular ...

Cultured mini-organs reveal the weapons of aggressive bacteria

The study opens the door to using cultured human mini-organs to investigate a wide range of other serious infections

16-Jun-2025 - Thanks to lab-grown miniature intestines, researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg in collaboration with Uppsala University in Sweden have successfully mapped how aggressive Shigella bacteria infect the human gut. The study, published in the ...

New Microscope Brings Glowing Cells into Focus

A New Tool for Studying Life in Motion

02-Jun-2025 - Researchers at Helmholtz Munich and the Technical University of Munich have developed a new microscope that significantly improves how bioluminescent signals in living cells can be observed. The system, known as QIScope, is built around a highly sensitive camera technology capable of detecting ...

Newly identified group of nerve cells in the brain regulates bodyweight

Potential for novel obesity treatments

30-May-2025 - Obesity is a global health problem that affects many people. In recent years, very promising anti-obesity drugs have been developed. Despite these successes, there are patients who do not respond to these drugs or suffer from side effects. Therefore, there is still an unmet need for therapies. ...

Sanofi to acquire Vigil Neuroscience, Inc., adding a new investigational medicine to treat Alzheimer’s disease to the neurology pipeline

26-May-2025 - Sanofi announced that it has entered into an agreement to acquire Vigil Neuroscience, Inc., a publicly traded clinical-stage biotechnology company focused on developing novel therapies for neurodegenerative diseases. This acquisition in neurology, one of Sanofi’s four strategic disease areas, ...

How aging changes the blood system

A few stem cells, or “clones”, outcompete their neighbours and gradually take over blood production

23-May-2025 - The reservoir of blood stem cells shrinks with age. It becomes increasingly dominated by stem cells that produce immune cells associated with chronic inflammation. Almost all of the 60-year-olds studied show this change. Researchers from the Centre for Genomic Regulation and the Institute for ...