New Bioactive Compound for Difficult-to-Treat Allergies

Study leads to the discovery of a promising receptor blocker

02-May-2025 - Irritable bowel syndrome, chronic itching, asthma and migraine are in many cases hard-to-treat conditions. They have in common that they are triggered by an excessive immune response—which in severe cases can be life-threatening. A team of researchers led by the University of Bonn has now ...

Power vaccination against cancer boosts the immune system

New hope: Researchers are mobilising the immune system's defence against tumour cells within just two weeks using a two-phase vaccination regimen

29-Apr-2025 - Our body's own defence system not only clears away bacteria and viruses, it can also fight cancer. However, not all tumour cells are easily recognisable by the immune system. In addition, they are constantly changing and camouflaging themselves to evade the defence system. In order to treat ...

New regulatory protein of the neuronal cytoskeleton identified

28-Apr-2025 - The growth and function of nerve cells is based on a lattice-like structure called membrane-associated periodic skeleton (MPS). However, how the organization of the MPS is controlled has not been elucidated until now. A team from the Max Planck Institutes for Medical Research and for ...

Better insights into the hepatitis D virus

Hannover researchers develop stem cell-based infection model

28-Apr-2025 - Hepatitis D virus (HDV) infects the liver and causes severe inflammation. According to WHO estimates, 12 million people worldwide are infected with HDV. Currently, there are only a few treatment options. A team of researchers from TWINCORE, the Centre for Experimental and Clinical Infection ...

How ibuprofen affects fat metabolism in the brain

Alzheimer's research: New in vitro laboratory study provides important insights

17-Apr-2025 - In a joint study, SRH University and Saarland University have found that the widely used painkiller ibuprofen affects the metabolism of certain fats in the brain. According to the World Health Organization (WHO), around 55 million people worldwide are affected by dementia, a large proportion of ...

Research breakthrough: Lab-grown teeth might become an alternative to fillings

This research offers a potential way to repair teeth and a natural dental treatment alternative

16-Apr-2025 - While some animals like sharks and elephants can continuously grow new teeth, humans only have one set from adulthood. The ability to regenerate teeth would be a major leap forward for dentistry. Unlike implants and fillings, which are fixed and cannot adapt over time, a lab-grown tooth made from ...

Engineering Smart Delivery for Gene Editors

Restoring Vision: New hope for genetic diseases and cancer therapies

11-Apr-2025 - A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than before. Their technology, ENVLPE, ...

What drives our cravings for food and drink?

New research shines light on how the brain interprets nutritional and hydration needs and turns them into action

02-Apr-2025 - To ensure we get the calories and hydration we need, the brain relies on a complex network of cells, signals, and pathways to guide us when to eat, drink, or stop. Yet, much about how the brain deciphers the body’s needs and translates them into action remains unknown. Researchers from the Max ...

mRNA-based COVID-19 vaccines train the ‘long-term memory’ of the immune system

Findings have far-reaching implications for the development of future vaccination strategie

28-Mar-2025 - Researchers at the University of Cologne and University Hospital Cologne have shown in their study that the novel mRNA-based COVID-19 vaccines not only induce acquired immune responses such as antibody production, but also cause persistent epigenetic changes in innate immune cells. The study ...

Nursery of the Blood: How Stem Cells Calm the Body’s Immune Response

The researchers uncovered an unexpected finding

28-Mar-2025 - Our blood consists of many cell types that develop through different stages from a precursor type – the blood stem cell. An international research team led by Universitätsmedizin Frankfurt and Goethe University has now investigated the developmental pathways of blood cells in humans. The results ...