Brain diseases - 51 News

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Brain diseases - 51 News

Tip: You can further refine your news selection by departments, organizations, countries and industries.

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Riddle of proteins in the brain solved

Erin Schuman awarded the Körber European Science Prize, worth one million euros

01-Jul-2024 - The American neurobiologist Erin Schuman is a pioneer in neurobiology. Schuman’s work has revolutionised our understanding of how individual brain cells – so called neurons – work. She discovered that and how proteins, as critical building blocks of the cells, are locally produced at the ...

brain diseases brain brain research
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PharmaKure announces collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases

New collaboration will enhance ability to identify those more at risk of developing brain diseases to enable earlier interventions

04-Mar-2024 - PharmaKure announces a new epigenetics collaboration with Sheffield Hallam University. This partnership will focus on ‘gene-based environmental biomarkers’, known as epigenetic markers, for calculating risk scores for Alzheimer’s diseases. Together withALZmetrixTM, PharmaKure’s blood-based ...

brain diseases Alzheimer's disease biomarkers
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Drug Testing with Artificial Brain Vessels

Screening method simulates filter effect of the “blood-brain barrier”

05-Sep-2022 - In the journal “Biomaterials”, DZNE researchers present a novel method for testing chemical agents that could help in the development of drugs against neurodegenerative diseases. This analytical technique allows to study in the laboratory whether new drug candidates have a realistic chance of ...

brain diseases blood-brain barrier brain
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Discovery of molecular signatures of immature neurons in the human brain provide new insights into brain plasticity

Analysis also shows severe reduction of these neurons in the brains of people with Alzheimer’s Disease

22-Jul-2022 - A team led by researchers at the Perelman School of Medicine at the University of Pennsylvania has used advanced techniques to show that, in a key memory region of the brain called the hippocampus, immature, plastic neurons are present in significant numbers throughout the human lifespan. The ...

brain diseases brain brain disorders
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More Brain Lesions in Senior Women than in Men of the Same Age

The Extent of Abnormalities in the Brain’s White Matter Grows Significantly After Menopause

04-Jul-2022 - In women after menopause, the extent of certain brain lesions is larger than in men of the same age. DZNE researchers come to this conclusion based on the assessment of more than 3,400 adults as part of the Bonn Rhineland Study. A team led by neuroscientist Monique Breteler reports on the ...

brain diseases brain circulatory disorders
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Inhaled toxic particles take direct route from lungs to brain

Once in the brain, the particles were hard to clear and were retained for longer than in other organs

22-Jun-2022 - Breathing in polluted air could lead to toxic particles being transported from lungs to brain, via the bloodstream – potentially contributing to brain disorders and neurological damage, a new study reveals. Scientists have discovered a possible direct pathway used by various inhaled fine ...

brain diseases air pollution bloodstream
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Rare discovery: How a gene mutation causes higher intelligence

“It’s very rare for a mutation to lead to improvement rather than loss of function”

11-May-2022 - When genes mutate, this can lead to severe diseases of the human nervous system. Researchers at Leipzig University and the University of Würzburg have now used fruit flies to demonstrate how, apart from the negative effect, the mutation of a neuronal gene can have a positive effect – namely ...

brain diseases gene mutations genes
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Why drugs sometimes cause receptor potentiation rather than inhibition

Some highly selective drugs cause unexpected effects in nerve cells: they not only reduce the activation of certain receptors, but also their inactivation

05-Oct-2020 - In order to treat certain brain diseases more precisely and with fewer side effects, researchers are focusing on drugs that only inhibit distinct subtypes of the receptors responding to the neurotransmitter glutamate. However, under certain conditions, such drugs can elicit the opposite effect: ...

brain diseases glutamate receptors receptors
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Lipid Metabolism Controls Brain Development

Diminished stem cell activity reduces cognitive performance

11-May-2020 - A lipid metabolism enzyme controls brain stem cell activity and lifelong brain development. If the enzyme does not work correctly, it causes learning and memory deficits in humans and mice, as researchers at the University of Zurich have discovered. Regulating stem cell activity via lipid ...

brain diseases brain development enzymes
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Nanodiamonds in the brain

Tiny diamonds can cross the blood-brain barrier and be used for diagnostic and therapeutic purposes in the brain

03-Sep-2019 - The recording of images of the human brain and its therapy in neurodegenerative diseases is still a major challenge in current medical research. The so-called blood-brain barrier, a kind of filter system of the body between the blood system and the central nervous system, constrains the supply of ...

brain diseases albumin biopolymers
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