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Fly models of Parkinson’s disease point way to new therapies

Celardi et al. "Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson’s disease" Cell Death and Disease (2016). doi:10.1038/cddis.2016.173

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    Deciphering the 'mosaic' of the brain

    Researchers from the University of Leicester have shed new light on how neurons in the brain communicate with one another. This could potentially help in our understanding of how and why a range of neurodegenerative diseases occur. The team, led by Dr Joern Steinert from the MRC Toxicology ... more

    Air pollution can alter effectiveness of antibiotics

    Air pollution can change the way bacteria behave and can change their potential to cause disease Interdisciplinary research discovers new mechanism of how air pollution is detrimental to our health and well-being Developing megacities with extreme levels of air pollution are major risk fact ... more

    Mysteries of enzyme mechanism revealed

    An international research team led by the University of Leicester has made a breakthrough advance by trapping an intermediate in the mechanism of enzymes called heme peroxidases and determining its structure using a beam of neutrons from the heart of a nuclear reactor. The Leicester team me ... more

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