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Effective therapeutics to counteract the formation of amyloid plaques in Alzheimer's disease and type 2 diabetes are not yet available. Scientists at the Technical University of Munich (TUM) have now come a little bit closer to a solution: They have described a new class of designed macrocyclic pep more
In diabetes, both the tightly woven endothelial cells that line our blood vessels and the powerhouses that drive those cells start to come apart as early steps in the destruction of our vasculature. Now scientists have evidence that these breakups occur as another relationship falls apart. Levels of more
Evotec AG announced that its strategic alliance (TargetBCD) with Sanofi in the field of diabetes has reached its second beta cell therapy milestone, resulting in a payment of € 3 million to Evotec. This milestone was triggered after Evotec met pre-agreed critical success criteria for a potential ma more
Here’s a mini-graphic taking a quick look at what diabetes is, and the differences between the three main types. more
Pharmaceuticals, Vol. 11, Pages 61: Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology Pharmaceuticals doi: 10.3390/ph11030061 Authors: Joaquim Aguirre-Plans Janet Piñero Jörg Menche Ferran Sanz Laura I. Furlong Harald H. H. W. Schmid more
Obesity has become a major epidemic around the globe, with fatal comorbidities such as type 2 diabetes, heart disease, and cancer that have led to alarming health concerns in modern medicine. Although excess adipose tissue is associated with negative metabolic outcomes, the physiological functions o more
Risk prediction of type 2 diabetes using common and rare variantsSunghwan Bae; Taesung ParkInternational Journal of Data Mining and Bioinformatics, Vol. 20, No. 1 (2018) pp. 77 - 90The recent development of next generation sequencing technology has led to the identification of several disease-relat more
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