Type 2 diabetes: Promising new active ingredient discovered without side effects for the heart and circulation

Improved effect of "weight loss injections"

04-Jul-2025 - In type 2 diabetes, formerly known as adult-onset diabetes, the body's cells are no longer able to absorb sugar from the blood. One possible therapeutic approach is therefore to increase glucose uptake in the cells again. Although it has been known for some time that the active ingredient class ...

Preventing harmful protein aggregation

Synthetic Peptides as basis for multifunctional drugs in Parkinson's disease

25-Apr-2025 - In Alzheimer's, Parkinson's, and type 2 diabetes, harmful protein aggregates and deposits, known as amyloid plaques, develop. There is also much evidence that these three diseases are interconnected and mutually reinforcing. A research team led by the Technical University of Munich (TUM) has now ...

New drug delivery system could reduce daily diabetes shots to just three a year

Dietary management drugs have transformed Type 2 diabetes care, but daily injection routines are challenging for some patients

23-Nov-2023 - Materials engineers at Stanford University have developed a novel hydrogel drug delivery system that transforms daily or weekly injections of diabetes and weight control drugs like Ozempic, Mounjaro, Trulicity, Victoza, and others to just once every four months. In a new study, researchers ...

Health effects of highly processed foods

Type 2 diabetes and diet: when the ready-made snack ruins the metabolism

31-Oct-2023 - Anyone dealing with type 2 diabetes cannot avoid the topic of nutrition - after all, a diet that is too rich and not very balanced is considered one of the main risk factors for the development of the metabolic disease. Highly processed foods are particularly problematic: they often contain too ...

Novel biomarker score could help measure adherence to Mediterranean diet

New evidence suggests Mediterranean diet may reduce type 2 diabetes risk more than previously thought

01-May-2023 - Researchers have developed a novel way to detect whether a person follows a Mediterranean diet using a blood test and, applying this method, have shown that a Mediterranean diet is associated with lower risk of type 2 diabetes. Jakub Sobiecki of the University of Cambridge, UK and colleagues ...

Synthetic peptides may suppress formation of harmful deposits

Valuable candidates for the development of drugs for treating Alzheimer's disease and type 2 diabetes

10-Nov-2022 - In Alzheimer's disease, the degeneration of brain cells is linked to formation of toxic protein aggregates and deposits known as amyloid plaques. Similar processes play an important role also in type 2 diabetes. A research team under the lead of the Technical University of Munich has now ...

Diabetes: When circadian lipid rhythms go wrong

A team from Geneva, Switzerland, shows that the disruption of lipid temporal profiles in type 2 diabetes stiffens the membrane of pancreatic endocrine cells, which could alter their function.

21-Sep-2022 - Like all living beings, human physiological processes are influenced by circadian rhythms. The disruption of our internal clocks due to an increasingly unbalanced lifestyle is directly linked to the explosion in cases of type 2 diabetes. By what mechanism? A team from the University of Geneva ...

Dairy products in moderate amounts may protect against type 2 diabetes – but red and processed meat raise risk, Italian research suggests

19-Sep-2022 - New research being presented at the annual meeting of the European Association for the Study of Diabetes in Stockholm, Sweden (19-23 Sept) shows that dairy products, especially low-fat ones and yogurt, are associated with a lower risk of developing type 2 diabetes (T2D). Red and processed meat ...

Obesity: Genetic predisposition as cause, drugs from diabetes therapy help

22-Jul-2022 - Severe overweight or obesity is one of the most important risk factors that can be influenced for the development of type 2 diabetes. Obesity, or severe overweight, often develops in sufferers during childhood and adolescence. Before 2020, one in seven children in Germany was obese - a trend that ...

A low-calorie diet alters the gut microbiome and delays immune aging

26-Apr-2022 - A calorie-reduced diet can not only delay the development of metabolic diseases, but also has a positive effect on the immune system. Researchers have now shown for the first time that this effect is mediated by an altered gut microbiome*, which slows down the deterioration of the immune system ...