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Codex® HiCap RNA Polymerase
Advanced IVT Enzymes for Scalable, High-Quality mRNA Production
Efficient capping. Better mRNA outcomes.
- Designed to enhance 5′ capping efficiency, supporting improved mRNA quality and translational performance
- Reduces double-stranded RNA formation compared to wild-type T7 polymerase, contributing to cleaner RNA profiles and reduced down-stream burden
- Optimized for integration into established IVT workflows, enabling consistent process performance without added complexity
- Delivers reproducible transcription outcomes across templates and scales, supporting reliable process development and scale-up
- Aligned with clinical and cGMP applications, enabling high-quality mRNA production from research through manufacturing
Improve mRNA quality at its source by enhancing in-vitro transcription performance with Aldevron’s line of products, headlined by our Codex® HiCap RNA Polymerase.
Codex® HiCap RNA Polymerase is an advanced IVT enzyme engineered to maximize 5′ capping efficiency while reducing double stranded RNA formation. By improving transcription quality during the IVT step, Codex® HiCap RNA Polymerase helps generate cleaner RNA profiles, supporting more efficient downstream processing and consistent product performance.
Designed for seamless integration into established IVT workflows, Codex®HiCap RNA Polymerase enables reliable transcription across templates and scales—without adding complexity. Its performance supports more predictable development, helping teams maintain RNA integrity while progressing from early-stage research through GMP-aligned manufacturing.
As part of Aldevron’s broader RNA platform, Codex®HiCap RNA Polymerase contributes to an optimized, end-to-end approach to mRNA production—linking upstream design with downstream quality and scalability.
Enhances IVT performance at the source
Driving higher 5′ capping and improved overall mRNA quality
Reduces double-stranded RNA formation
Supporting cleaner RNA profiles and lowering downstream purification burden
Delivers consistent transcription performance
Reducing variability and the risk of uncapped or improperly capped transcripts
Integrates into existing IVT workflows
Maintaining process continuity without additional complexity
Supports scalable, cGMP-aligned production
Enabling progression from development to clinical manufacturing with confidence
Request information about Codex® HiCap RNA Polymerase now
Catalog: Codex® HiCap RNA Polymerase
Advanced IVT Enzymes for Scalable, High-Quality mRNA Production
Product classification Codex® HiCap RNA Polymerase
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Topic world Gene therapy
Genetic diseases once considered untreatable are now at the center of innovative therapeutic approaches. Research and development of gene therapies in biotech and pharma aim to directly correct or replace defective or missing genes to combat disease at the molecular level. This revolutionary approach promises not only to treat symptoms, but to eliminate the cause of the disease itself.
Topic world Gene therapy
Genetic diseases once considered untreatable are now at the center of innovative therapeutic approaches. Research and development of gene therapies in biotech and pharma aim to directly correct or replace defective or missing genes to combat disease at the molecular level. This revolutionary approach promises not only to treat symptoms, but to eliminate the cause of the disease itself.