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CTech SoloVPE Variable Pathlength Spectroscopy System

CTech SoloVPE System – Variable Pathlength Spectroscopy for Rapid Concentration Measurement

Repligen Corporation

No dilution needed—Direct sample measurement with no sample prep/dilution required

Results in < 1 minutes—avoid delays, rapidly identify issues, and keep your process moving forward

Increased accuracy—Multiple absorbance slope-based concentration measurements based on R2 ≥ 0.999

Higher Accuracy. Faster Results. Better Data

The CTech SoloVPE System leverages the power and flexibility of variable pathlength technology to create a rapid, robust, and repeatable concentration measurement method for proteins, plasmid DNA and other nucleic acid modalities, with results in minutes, not hours.

Traditional UV-Vis spectrophotometers require a number of operator steps to measure concentration and generate a single absorbance point. The SoloVPE System using variable pathlength technology generates multiple auto-calibrated measurements of undiluted, true material for an accurate slope-based concentration result.

The system’s slope-based measurement, confirmed with R2 ≥ 0.999, reduces potential user error and ensures accurate results. Proven repeatability of ±2% from system-to-system, operator-to-operator, and site-to-site for a wide range of sample concentrations (0.01-300 mg/mL)

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CTech SoloVPE System – Variable Pathlength Spectroscopy for Rapid Concentration Measurement

Click on images for larger views

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The fiber optic is connected to a linear stage that moves up and down through your sample, changing the pathlength anywhere from 1 micron to 15 mm.

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The concentration is a fixed value and does not require sample dilution. Multiple absorbance measurements taken in under 1 min.

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Pathlength (l) is a variable value, capturing multiple absorbance measurements in less than 1 minute

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Various vessel sizes to meet your testing requirements.

Product classification

Applications

AAV viral titer
Antibody Drug Conjugates (Drug-to-Antibody Ratio)
Antisense oligonucleotide concentration measurement
gold particle testing/Planova integrity testing
multicomponent analysis
OD600 monitoring
plasmid DNA purity ratio
polysorbate analysis
protein concentration measurement (A280)
quantitation of nucleic acids (DNA/RNA)

Product categories

concentration measurement devices
process analytics instruments
slope spectroscopy
ultra-violet visible spectrophotometers
uv-vis spectroscopy
variable pathlength spectroscopy

Target Industries

Biotechnology
Pharma

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CTech SoloVPE Variable Pathlength Spectroscopy System

CTech SoloVPE System – Variable Pathlength Spectroscopy for Rapid Concentration Measurement