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ÄKTA Protein Purification Systems – Easy to Use Benchtop Systems to Accelerate Daily Routines

Designed for purification of biomolecules, providing speed, performance, and flexibility in research and process development more

News Peptides

• Useful “Fake” Peptides
  

  Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units. These oligoureas, which are composed of urea-based units, fold into a structure similar to that of more

• What social distancing does to a brain
  

  An international research team led by Erin Schuman from the Max Planck Institute for Brain Research discovered a brain molecule that functions as a “thermometer” for the presence of others in an animal’s environment. Zebrafish “feel” the presence of others via mechanosensation and water movements - more

• Beetroot peptide as potential drug candidate for treating neurodegenerative and inflammatory diseases
  

  In a recent study, a research group led by Christian Gruber at MedUni Vienna's Institute of Pharmacology isolated a peptide (small protein molecule) from beetroot. The peptide is able to inhibit a particular enzyme that is responsible for the breakdown of messenger molecules in the body. Due to its more

Videos Peptides

ÄKTA Protein Purification Systems – Easy to Use Benchtop Systems to Accelerate Daily Routines

ÄKTA™ lab-scale protein purification systems are designed for purification of biomolecules, providing speed, performance, and flexibility in research and process development. ÄKTA systems use intelligent UNICORN™ system control software to combine simplicity with power in protein purification from y more

White papers Peptides

• Agrisera Western Blot recommendations, troubleshooting and protocol
  

  Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more

• Method for Producing reduced Glycans and Glycan-arrays
  

  The invention presented here provides an improved method for the preparation of multiple types of glycans and their usage more

• Increased productivity for downstream processing of biotherapeutics
  

  Polymer-based chromatographic resins featuring high mechanical and chemical stability and high protein binding capacities can help to increase the thr more

Infographics Peptides

A Brief Overview of Classes of Antibiotics

When we’re suffering from a bacterial infection, a trip to the doctors to be prescribed antibiotics is commonplace. However, there are a wide range of antibiotics available, and they vary both in their usage and their mechanism of action. This graphic summarises the major classes, and also gives a b more

The Chemistry of Spider Venom

Spider venoms can be grouped into two broad categories: necrotic, and neurotoxic. Necrotic, or cytotoxic venoms, are those which cause cell and tissue damage after envenomation. This can lead to the appearance of inflammation, lesions, and blisters. Neurotoxic venoms, on the other hand, exert their more

Harnessing evolution to produce new enzymes and antibodies

The last of the 2018 Science Nobel Prizes is awarded, and it was finally the turn of chemistry. The 2018 Nobel Prize in Chemistry was awarded with one half to Frances H Arnold for her work on the directed evolution of enzymes, and with the other half jointly to George P Smith and Sir Gregory P Winte more

Publications Peptides

• Marine Drugs, Vol. 16, Pages 220: Cyanopeptolins with Trypsin and Chymotrypsin Inhibitory Activity from the Cyanobacterium Nostoc edaphicum CCNP1411

  Marine Drugs, Vol. 16, Pages 220: Cyanopeptolins with Trypsin and Chymotrypsin Inhibitory Activity from the Cyanobacterium Nostoc edaphicum CCNP1411 Marine Drugs doi: 10.3390/md16070220 Authors: Hanna Mazur-Marzec Anna Fidor Marta Cegłowska Ewa Wieczerzak Magdalena Kropidłowska Ma more

• Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens

  by Daniel Pletzer, Sarah C. Mansour, Robert E. W. Hancock With the antibiotic development pipeline running dry, many fear that we might soon run out of treatment options. High-density infections are particularly difficult to treat due to their adaptive multidrug-resistance and currently there are more

• Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking [Biochemistry]

  Beclin 1 is an essential autophagy protein. Through its coiled-coil domain, Beclin 1 recruits two modulators, Atg14L and UVRAG, to form Atg14L- or UVRAG-containing Beclin 1–Vps34 subcomplexes responsible for Vps34-dependent membrane trafficking processes including autophagy and endosomal trafficking more