Nicotine

News Nicotine

• Humans transport dangerous smoke residues indoors
  

  Decades of research have demonstrated the adverse effects of fine particulate matter and volatile organic compounds (VOC) such as nicotine or acetonitrile from tobacco smoke on human health, with no “safe” level of exposure. Smoking restrictions have decreased non-smokers’ exposure to secondhand smo more

• Study finds electronic cigarettes damage brain stem cells
  

  A research team at the University of California, Riverside, has found that electronic cigarettes, often targeted to youth and pregnant women, produce a stress response in neural stem cells, which are critical cells in the brain. Present throughout life, stem cells become specialized cells with more more

• Breakthrough in mapping nicotine addiction could help researchers improve treatment
  

  A scientific blueprint to end tobacco cravings may be on the way after researchers crystallized a protein that holds answers to how nicotine addiction occurs in the brain. The breakthrough at the Peter O'Donnell Jr. Brain Institute comes after decades of failed attempts to crystallize and determine more

Infographics Nicotine

The Chemicals in Cigarette Smoke & Their Effects

That smoking causes cancer is a well known and scientifically proven fact. Everyone knows that nicotine is present in cigarettes, and causes addiction to smoking; however, what’s a little less well known is the range of chemicals contained within cigarette smoke that can lead to carcinogenic (cancer more

Publications Nicotine

• Reply to Queimado et al.: E-cigarettes induce DNA damage and inhibit DNA repair in mice and human cells [Biological Sciences]

  We believe that Queimado et al. (1) may have inadvertently missed several key details presented in our recent PNAS publication (2). First, for the determination of nicotine effects on DNA adduct formation and DNA repair activity, the nicotine concentrations used for 1-h treatments of human lung and more

• Effects of alcohol dependence on discrete choice between alcohol and saccharin

  Dependence on drugs has enduring effects on drug intake and relapse. The role of choice in enhanced susceptibility to drug use in drug dependence has been little studied. Here we determine the effects of alcohol dependence on the choice between alcohol and a non-drug reward, saccharin, using the dis more

• Generalized extracellular molecule sensor platform for programming cellular behavior

  Strategies for expanding the sensor space of designer receptors are urgently needed to tailor cell-based therapies to respond to any type of medically relevant molecules. Here, we describe a universal approach to designing receptor scaffolds that enables antibody-specific molecular input to activate more