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18-May-2017 - An international team including researchers from MIPT has shown that iodide phasing--a long-established method in structural biology--is universally applicable to membrane protein structure determination. Knowledge of these structures enables a molecular-level understanding of the workings of ...
10-Apr-2017 - Some sea creatures cover themselves with hard shells and spines, while vertebrates build skeletons out of the same minerals. How do these animals get the calcium they need to build these strong mineral structures? Professors Lia Addadi and Steve Weiner of the Weizmann Institute of Science's ...
08-Mar-2017 - A team of scientists from the Laboratory for Advanced Studies of Membrane Proteins at MIPT, Research Center Jülich (Germany), and Institut de Biologie Structurale (France) have developed a new approach to membrane protein crystallization. For the first time, the scientists showed that membrane ...
03-Mar-2017 - Using 3D electron microscopy, structural biologists from the University of Zurich succeeded in elucidating the architecture of the lamina of the cell nucleus at molecular resolution for the first time. This scaffold stabilizes the cell nucleus in higher eukaryotes and is involved in organizing, ...
15-Feb-2017 - An international team of scientists has used high-intensity X-ray pulses to determine the structure of the crystalline protein envelope of an insect virus. Their analysis reveals the fine details of the building blocks that make up the viral cocoon down to a scale of 0.2 nanometres (millionths of ...
25-Jan-2017 - Using a state-of-the-art imaging technology in which molecules are deep frozen, scientists in Roderick MacKinnon 's lab at Rockefeller University have reconstructed in unprecedented detail the three-dimensional architecture of three channels that provide a path for specific types of ions to ...
21-Dec-2016 - Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease. Knowing the shape of the molecule -- and how that shape may be disrupted by certain genetic mutations -- can help in understanding how ...
06-Dec-2016 - Ribosomes--macromolecular machines consisting of RNA and proteins that twist, fold and turn--are responsible for making all of the protein within a cell and could hold the key to deciphering a range of diseases. Despite the intricacies of ribosomes, cells are able to churn out 100,000 of them ...
25-Nov-2016 - The brightest red fluorescent protein ever, mScarlet, has just been engineered by researchers at the University of Amsterdam, the Institut de Biologie Structurale, IBS (CEA/CNRS/University Grenoble Alpes) and the European Synchrotron (ESRF) in France. mScarlet can be used to monitor the activity ...
26-Aug-2016 - Integral Molecular announced a major advancement in understanding the functionality of G protein-coupled receptors (GPCRs), the largest protein superfamily in the human genome, providing unprecedented insight for human disease therapeutics. The work answers the fundamental question of how GPCRs, ...
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