Innovative technology for the enrichment of free-circulating DNA

13-Jan-2014 - After a two year period of development Analytik Jena has launched an innovative technology to enrich and isolate free-circulating DNA. Free-circulating DNA occurs in plasma, serum, and urine, among other things, but only in small fragments and very low concentrations. In order to isolate them, ...

PRAC considers benefits of Kogenate Bayer/Helixate NexGen outweigh risks in previously untreated patients

Current evidence does not confirm increased risk of inhibitor development compared with other factor VIII products

10-Dec-2013 - The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has reviewed the medicines Kogenate Bayer and Helixate NexGen and concluded that current evidence did not confirm an increased risk of developing antibodies (factor VIII inhibitors) against these medicines when ...

Biomarkers for early malaria diagnosis

22-May-2013 - Scientists in Japan have developed a technique that could be used to diagnose malaria using a blood plasma sample just one day after infection. It is vital to diagnose malaria as soon as possible to maximise the effectiveness of treatment. Currently, light microscopy is the main technique used ...

Counting copy numbers characterizes prostate cancer

08-Apr-2013 - Non-invasive 'liquid biopsies' can find metastatic or recurrent prostate cancer, in a low cost assay suitable for most healthcare systems, finds research published in Genome Medicine. Genomic signatures of prostate cancer, isolated from plasma DNA, display abnormal copy numbers of specific areas ...

Increasing surgical volumes to boost use of tissue sealants and topical haemostats, says Frost & Sullivan

13-Feb-2013 - The need for quality care, especially for a rapidly ageing population, is a strong driving factor for the tissue sealants and haemostats market in Western Europe. Technologically advanced products that enhance surgical efficiency and patient safety will also boost market prospects. New analysis ...

How pathogens hijack host plants

29-Nov-2010 - Infestation by bacteria and other pathogens result in global crop losses of over $500 billion annually. A research team led by the Carnegie Institution's Department of Plant Biology developed a novel trick for identifying how pathogens hijack plant nutrients to take over the organism. They ...

Initiation of a Phase II clinical trial with anti-KIR monoclonal antibody IPH 2101 in smoldering myeloma patients

25-Nov-2010 - Innate Pharma announced that it has started patient inclusion in a new multicenter Phase II clinical trial with IPH 2101, an anti-KIR monoclonal antibody potentiating the anti-tumor activity of NK cells. In this trial, IPH 2101 is tested as a single agent in patients with smoldering myeloma, an ...

Excellent early results in large OvPlex ovarian cancer biomarker study

16-Nov-2010 - Stage 1 of HealthLinx Limited’smulti-centre, multi-site second study for OvPlex™ has returned excellent initial data for the two new biomarkers AGR2 and HTX010 being evaluated for accuracy in diagnosing ovarian cancer. To date, AGR2 and HTX010 data have been analysed in over 400 case and control ...

Amsterdam Molecular Therapeutics Successfully Lowers Cholesterol In Vivo with Enhanced Novel MicroRNA AAV Gene Therapy

27-Oct-2010 - Amsterdam Molecular Therapeutics (AMT) Holding N.V. announced that its gene therapy product incorporating siRNA sequences into microRNA scaffolds to silence Apolipoprotein B100 (AAV-miApoB) was able to significantly lower plasma cholesterol levels in vivo over a period of 18 weeks. These ...

Amsterdam Molecular Therapeutics Successfully Lowers Cholesterol In Vivo with Enhanced Novel MicroRNA AAV Gene Therapy

26-Oct-2010 - Amsterdam Molecular Therapeutics (AMT) Holding N.V. announced that its gene therapy product incorporating siRNA sequences into microRNA scaffolds to silence Apolipoprotein B100 (AAV-miApoB) was able to significantly lower plasma cholesterol levels in vivo over a period of 18 weeks. These ...