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669 Current news about the topic genetics


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Rare inherited variants in previously unsuspected genes may confer significant risk for autism

New Study in Nature Genetics uses SPARK database to investigate variants that are less damaging than de novo mutations, but contribute almost as much risk


Researchers have identified a rare class of genetic differences transmitted from parents without autism to their affected children with autism and determined that they are most prominent in "multiplex" families with more than one family member on the spectrum. These findings are reported in ...


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Geneticists reveal how mutation causes childhood cancer

Use drug to reverse its effects


Geneticists from Trinity College Dublin have discovered how a specific genetic mutation called H3K27M causes a devastating, incurable childhood cancer, known as diffuse midline glioma (DMG), and - in lab studies working with model cell types - successfully reverse its effects to slow cancer cell ...


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How environmental influences could keep the brain young


Stimulating life circumstances keep the "hippocampus" - the control center of memory located in the brain - young, so to speak. This is due to molecular mechanisms that affect gene control. These current findings from studies on mice provide clues as to why an active, varied life can help to ...


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Optogenetic methods restore partial vision in a blind patient

Milestone towards a gene therapy that could restore vision


An international research team has shown that optogenetic therapy has helped to partially regain visual function in a patient with retinitis pigmentosa. This is a milestone towards a gene therapy that could restore vision. Clinical trial results show for the first time that optogenetic methods ...


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How chemicals in plastic may cause lower IQ levels

The effects of environmental chemicals at the molecular level


The chemical bisphenol F (found in plastics) can induce changes in a gene that is vital for neurological development. This discovery was made by researchers at the universities of Uppsala and Karlstad, Sweden. The mechanism could explain why exposure to this chemical during the fetal stage may be ...


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Espresso, latte or decaf? Genetic code drives your desire for coffee

How much coffee we drink is likely to be an indicator of our cardio health


Whether you hanker for a hard hit of caffeine or favour the frothiness of a milky cappuccino, your regular coffee order could be telling you more about your cardio health than you think. In a world first study of 390,435 people, University of South Australia researchers found causal genetic ...


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Optogenetics: Light Regulates an Enzyme

New tool for cell biology: Würzburg researchers have developed a light sensor with an enzyme function that can be switched on and off with different light colours


The unicellular green alga Chlamydomonas reinhardtii has already given research a massive boost: One of its light sensors, channelrhodopsin-2, founded the success of optogenetics about 20 years ago. In this technology, the alga's light sensor is incorporated into cells or small living organisms ...


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Blood group co-determines composition of the intestinal microbiome

In a large genome study, a research team demonstrates correlations between certain gene variants and the composition of bacterial colonization in the human body


For several years, scientists worldwide have been investigating the extent to which microorganisms living in and on the human body influence central life processes and thus health and disease. Today they assume that there is a connection between the totality of the microbial colonization in the ...


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Genes could be key to new Covid-19 treatments

Five genes partially explain why some people become desperately sick with Covid-19, while others are not affected


Potential treatments for Covid-19 have been identified after the discovery of five genes associated with the most severe form of the disease. Genetic evidence is second only to clinical trials as a way to tell which treatments will be effective in a disease. Existing drugs that target the actions ...


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Genetics and intestinal microbiome determine susceptibility to multiple sclerosis

Study shows the link between genetics, intestinal microbiome and multiple sclerosis in mice for the first time


Multiple sclerosis (MS) is an autoimmune disease of the nervous system which affects more than two million people worldwide. In the course of the disease, the immune system attacks the insulation layer of nerve cells, and centers of inflammation develop in the brain and spinal cord, which over ...


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