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02-Jul-2021 - Stimulating life circumstances keep the "hippocampus" - the control center of memory located in the brain - young, so to speak. This is due to molecular mechanisms that affect gene control. These current findings from studies on mice provide clues as to why an active, varied life can help to ...
Chronobiologists report that soil bacteria possess an internal clock
14-Jan-2021 - Biological processes in many organisms are known resonate with natural rhythms. For instance, it is well known that cellular functions in plants and animals are regulated by an internal ‘circadian’ clock mechanism. Circadian clocks synchronize to environmental cycles such as the natural ...
05-Aug-2020 - The study of cellular dynamics is crucial to understand how cells develop and how diseases progress. Scientist at Helmholtz Zentrum München and Technical University of Munich (TUM) created “scVelo” – a machine learning method and open source software to estimate the dynamics of gene activity in ...
22-Nov-2019 - A three-dimensional computer model enables scientists to quickly determine which genes are active in which cells, and their precise location within an organ. A team led by Nikolaus Rajewsky, Berlin, and Nir Friedman, Jerusalem, has published the new method and their insights gained from this in ...
Reduced food intake in old mice can no longer improve health
24-Oct-2019 - Reduced food intake helps both animals and humans to improve health in old age and can prolong life. But when do you have to change your diet to achieve this benefit in old age? Scientists from the Max Planck Institute for Biology of Ageing, the Excellence Cluster for Ageing Research at the ...
An innovative method identifies newly activated genes within individual cells
12-Jul-2019 - Cells are equipped with multiple defense mechanisms to fight off intruders. Genes encode the building blocks of the response that must be activated during an enemy attack in an ordered manner. Scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, one of the ...
28-Jun-2019 - For the first time, researchers have decoded the genetic programmes that control the development of major organs in humans and other selected mammals – rhesus monkeys, mice, rats, rabbits, and opossums – before and after birth. Using next-generation sequencing technologies, the molecular ...
01-Mar-2019 - Aging promotes lung function decline and increases susceptibility to diseases of the respiratory tract. In order to understand these effects in detail, researchers at Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL), analyzed the aging process in the lung at ...
08-Nov-2018 - Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells. Scientists at Helmholtz Zentrum München have now discovered new ...
Biochemists discover cause of genome editing failures
13-Jul-2018 - Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient. CRISPR is a gene-editing tool that allows scientists to cut out unwanted genes or genetic material from DNA, ...
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