Atlas of older brains could help diagnosis of Alzheimer's disease

26-Jun-2015 - A digital map of the ageing brain could aid the diagnosis of Alzheimer's disease and other neurodegenerative disorders in older people, a study suggests.The atlas created using images from MRI scans of older people could aid diagnosis by comparing the patients' scans with a detailed map of the ...

Brain inflammation targeted in first drug discovery project from £3m Dementia Consortium

23-Jun-2015 - Funding worth nearly half a million pounds will unite academics at the University of Southampton with drug discovery experts at the medical research charity MRC Technology, to target the immune system in the hunt for new treatments for Alzheimer's disease.The work is the first to be funded by the ...

Heptares: Positive outcome from clinical study with first ever selective M1 agonist in Alzheimer's disease

22-Jun-2015 - Heptares Therapeutics announced the positive outcome of its Phase 1a study with HTL9936, the first-ever fully selective muscarinic M1 receptor agonist to enter clinical development.“HTL9936 was designed and developed specifically to be a first-in-class oral agent to improve cognitive function ...

Blood protein may indicate risk of Alzheimer's disease

22-Jun-2015 - Scientists at King's College London have identified a single blood protein that may indicate the development of Mild Cognitive Impairment (MCI) years before symptoms appear, a disorder that has been associated with an increased risk of Alzheimer's disease or other dementias.The new research, ...

New insights could result in changes to the therapeutic strategy to combat Alzheimer’s

​System developed for this research that could reduce a number of animal tests.

28-May-2015 - A typical characteristic of the brain of an Alzheimer sufferer is the presence of insoluble Tau protein aggregates. Scientists at VIB, KU Leuven and Janssen Pharmaceutica have demonstrated that the distribution of these aggregates through the brain is facilitated by synaptic connections between ...

Scientists find new link between diabetes and Alzheimer's

06-May-2015 - Researchers have uncovered a unique connection between diabetes and Alzheimer's disease, providing further evidence that a disease that robs people of their memories may be affected by elevated blood sugar, according to scientists at Washington University School of Medicine in St. Louis.While ...

Protecting against memory loss with olives

24-Mar-2015 - It has long been proven that people who follow a Mediterranean diet and keep physically and mentally active are less likely to suffer from dementia. Olives in particular appear to play a key role in this regard. But just what are the substances contained in these small, oval fruit that are so ...

AbbVie And C2N Enter Into A Worldwide License Agreement For Alzheimer's Disease Therapy

23-Mar-2015 - AbbVie announced that it has entered into an exclusive worldwide license agreement with C2N Diagnostics to develop and commercialize a portfolio of anti-tau antibodies for the treatment of Alzheimer's Disease and other neurological disorders. This partnership builds upon AbbVie's commitment to ...

Boosting a natural protection against Alzheimer's disease

Combining investigational therapy with gene variant may reduce dangers from debilitating brain plaques

16-Mar-2015 - Researchers at the University of California, San Diego School of Medicine have identified a gene variant that may be used to predict people most likely to respond to an investigational therapy under development for Alzheimer's disease (AD). The study, published March 12 in Cell Stem Cell, is ...

Amyloid formation may link Alzheimer disease and type 2 diabetes

18-Feb-2015 - The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D). However, little is known about whether different forms of amyloid proteins interact or how ...