How neuronal activity leads to Alzheimer's protein cleavage
23-Oct-2008 -
Amyloid precursor protein (APP), whose cleavage product, amyloid-b (Ab), builds up into fibrous plaques in the brains of Alzheimer's disease patients, jumps from one specialized membrane microdomain to another to be cleaved, report Sakurai et al.
Although there is no definitive evidence that Ab ...
Alzheimer's disease
cholesterol
exocytosis
+3