RNA - 6 News by Helmholtz-Institut für RNA-basierte Infektionsforschung (HIRI)
Interrogating disease progression and cell processes with TIGER: in vivo and non-invasively
Peering into the cellular past: Technology records ribonucleic acids in individual living cells.
11-Jan-2023 - Do we simply ingest a diagnostic probiotic based on programmed ribonucleic acids to analyze the intestinal health from individual cells in the future? Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Julius-Maximilians-Universität (JMU) in Würzburg have ...
Change with age: As bats mature their immune cells differ
Study unveils complexity of leukocytes in Egyptian fruit bat and its imprinting by age
08-Sep-2022 - A team of researchers led by Anca Dorhoi at the Friedrich-Loeffler-Institut (FLI) and Emmanuel Saliba at the Helmholtz Institute for RNA-based Infection Research (HIRI), has elucidated age-dependent variations in cellular immunity in Rousettus aegyptiacus, known as the Egyptian fruit bat, a ...
New “decision aid” for CRISPR immune responses
Scientists show that target RNA levels influence defense against invaders
15-Jun-2022 - Friend or foe? Immune systems constantly face this question. They must recognize and clear foreign invaders without eliciting autoimmunity. Prokaryotic CRISPR-Cas systems recognize invaders based on genetic sequence. But what happens if the host genome shares the same sequences? A research team ...
New CRISPR element regulates viral defense
Mechanism for prioritizing the immune response discovered
22-Mar-2022 - What tasks need to be done today, and which is the most urgent? People have to constantly set priorities in their daily life. Bacteria are no different: They too must prioritize when combating viruses with CRISPR. However, it was unclear how this prioritization takes place. Scientists from the ...
A sponge playing in defence
Bacteria are extremely resourceful when it comes to adapting to a given environment: A team of researchers has now discovered a new trick
09-Feb-2022 - Each year, at least 1.27 million people die from an infection with bacteria that are resistant to standard antibiotics, a study recently published in the journal The Lancet reveals. The authors fear that this number could rise to as many as ten million people by 2050. This makes the hunt for new ...
Researchers visualize the battle between virus and host cells at the single-cell level
An innovative method identifies newly activated genes within individual cells
12-Jul-2019 - Cells are equipped with multiple defense mechanisms to fight off intruders. Genes encode the building blocks of the response that must be activated during an enemy attack in an ordered manner. Scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, one of the ...
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