Protein complex key in avoiding DNA repair mistakes, cancer
Lymphoma and other cancers may occur when a delicate gene recombination process in antibody-making cells goes awry
06-Aug-2009 -
As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows. The discoveries in mice, published in Nature Structural and Molecular Biology, advance ...
antibodies
diffuse large B-cell lymphoma
DNA damage
+8