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Malaria pathogens under the X-ray microscope

X-ray microscopy at BESSY II reveals how antimalaria-drugs might work

04-Nov-2019

Malaria is one of the most threatening infectious diseases in the world. An international team has now been able to investigate malaria pathogens in red blood cells in vivo using the BESSY II X-ray microscope and the ALBA and ESRF synchrotron sources. The scientists reveal the mechanisms used by ...

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New discoveries map out CRISPR-Cas defence systems in bacteria

26-Sep-2019

With the aid of highly advanced microscopes and synchrotron sources, researchers from the University of Copenhagen have gained seminal insight into how bacteria function as defence mechanisms against attacks from other bacteria and viruses. The study, which has just been published in the journal, ...

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Little Heaps of Silver, All Wrapped Up

Determination of the crystal structure of a DNA-stabilized silver nanocluster

13-Sep-2019

Nanoclusters are little “heaps” of a few atoms that often have interesting optical properties and could become useful probes for imaging processes in areas such as biomedicine and diagnostics. In the journal Angewandte Chemie, researchers have introduced a nanocluster of 16 silver atoms ...

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Fine-tuning the gene scissors CRISPR

04-Dec-2018

The introduction of the tool for gene editing, the so-called gene scissors CRISPR, in 2007 was a revolution within medical science and cell biology. But even though the perspectives are great, the launch of CRISPR has been followed by debate, especially focussing on ethical issues and the ...

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Major study identifies new hay fever risk genes

19-Jul-2018

In a large international study involving almost 900,000 participants, researchers from the University of Copenhagen and COPSAC have found new risk genes for hay fever. It is the largest genetic study so far on this type of allergy, which affects millions of people around the world. Hay fever is ...

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Study offers new hope for the fight against genetically determined obesity

04-Jun-2018

Around two to six per cent of all people with obesity develop obesity already in early childhood; it's in their genetic cards. Obesity-causal mutations in one of their 'appetite genes' gives them a strong genetic predisposition for developing obesity, also called monogenic obesity. Their ...

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A power failure in your fat cells could short-circuit your health

04-Jun-2018

A specialized fat molecule, called cardiolipin, that is made within the body's own fat cells, is far more significant to the body's overall state of health than previously realized. Large amounts of cardiolipin produced in the fat cells' mitochondria - or so-called powerhouses - result in ...

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Challenging counterfeit products with rare earths

New marking technique could halt product piracy

29-Jan-2018

Researchers at the University of Copenhagen have developed the world's most secure marking system for combatting pirated goods including pirated pharmaceuticals, foodstuffs, designer merchandise and artwork. The system could be on the market in a year and because the markings are random, it ...

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Searching for the CRISPR Swiss-army knife

13-Dec-2017

Scientists at the University of Copenhagen, led by the Spanish Professor Guillermo Montoya, are investigating the molecular features of different molecular scissors of the CRISPR-Cas system to shed light on the so-called 'Swiss-army knives' of genome editing. Montoya's research group has ...

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New vaccine technique effectively fights breast cancer in mice

04-Dec-2017

A new vaccine technique can fight a certain type of breast cancer in mice. So-called HER2-positive breast cancer accounts for between 20 and 30 per cent of all cases of breast cancer in humans. Researchers from the University of Copenhagen and the University of Bologna now show that the same type ...

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