Modifiable risk factors responsible for half of cardiovascular diseases

Regional differences in risk factors

29-Aug-2023 - Scientists of the Global Cardiovascular Risk Consortium under the auspices of the Department of Cardiology at the University Heart & Vascular Center of the Medical Center Hamburg-Eppendorf (UKE) and the German Center for Cardiovascular Research (DZHK) have proven that the five classic ...

A promising investigational therapeutic monoclonal antibody to treat chronic hepatitis B and D infections

08-Aug-2023 - Affecting hundreds of millions of people, chronic hepatitis B is a widespread global health problem for which there is as yet no cure. In a preclinical study involving the German Center for Infection Research (DZIF), Heidelberg University Hospital, University Medical Center Hamburg-Eppendorf and ...

T-cell immune response can control SARS-CoV-2 virus replication in immunocompromised patients

18-Jul-2022 - In a case study, scientists of the German Center for Infection Research (DZIF) and the University Medical Center Hamburg-Eppendorf investigated the T-cell response of a cancer patient, who was suffering from prolonged COVID-19. No B cells were detectable in the patient’s peripheral blood, ...

Adipose tissue is an important SARS-CoV-2 replication site

Obesity is an important risk factor for severe disease progression in COVID-19 patients

17-Dec-2021 - A multidisciplinary research team from the Leibniz Institute for Experimental Virology (HPI) and the University Medical Center Hamburg-Eppendorf (UKE) has now demonstrated an important role of adipose tissue in the viral replication of SARS-CoV-2. The results, which also identify new therapeutic ...

Taking the brain out for a walk

A recent study shows that spending time outdoors has a positive effect on our brains

21-Jul-2021 - If you’re regularly out in the fresh air, you’re doing something good for both your well-being and your brain. This is the conclusion reached by researchers at the Max Planck Institute for Human Development and the Medical Center Hamburg-Eppendorf. During the Corona pandemic, walks became a ...

New combination therapy offers chance of curing hepatitis B

08-Feb-2021 - Around 260 million people, more than three percent of the world's population, are chronically infected with the hepatitis B virus (HBV); in the long term, this often leads to complications such as cirrhosis of the liver or liver cancer. A cure is not yet possible with existing drugs. Scientists ...

Scientists grow 3D human heart muscle from skin cells

18-Dec-2018 - New German research shows that beating human heart muscle can be grown in a laboratory from donated skin cells. The study, published in Stem Cell Reports and part-funded by the German Centre for Cardiovascular Research (DZHK), could lead to personalised treatments for heart conditions like atrial ...

Successes with heart tissue patches from the lab

04-Nov-2016 - Myocardial patches generated in the lab can be grafted on to damaged guinea pig hearts to improve heart function. That is what a team of researchers from Germany, Norway, Scotland and the USA found out. Zebra fish and a few amphibian species can do it, mammals and humans cannot: that is replace ...

Counting copy numbers characterizes prostate cancer

08-Apr-2013 - Non-invasive 'liquid biopsies' can find metastatic or recurrent prostate cancer, in a low cost assay suitable for most healthcare systems, finds research published in Genome Medicine. Genomic signatures of prostate cancer, isolated from plasma DNA, display abnormal copy numbers of specific areas ...

ATI Neurostimulation System shown to be effective in treating cluster headache

Results of a multi-centre European study

07-Feb-2013 - Autonomic Technologies, Inc. (ATI) announced results of their clinical study in cluster headache. The ATI Neurostimulation System includes a novel, miniaturized device that is implanted using oral surgery, leaving no externally visible scars. When the patient feels a cluster attack beginning, ...