Changing stem cell structure may help fight obesity

18-Feb-2015 - The research, conducted at Queen Mary University of London (QMUL), found that a slight regulation in the length of primary cilia, small hair-like projections found on most cells, prevented the production of fat cells from human stem cells taken from adult bone marrow.Part of the process by which ...

Scientists discover new inflammatory target

Tiny organelles called primary cilia hold the key to combat inflammation

11-May-2012 - Scientists from Queen Mary, University of London have found a new therapeutic target to combat inflammation.The research, published in the journal Cellular and Molecular Life Sciences, revealed tiny organelles called primary cilia are important for regulating inflammation. The findings could lead ...

Protein found to regulate spread of pancreatic cancer cells

27-Mar-2012 - Researchers at Queen Mary, University of London have identified a new protein that makes pancreatic cancer cells less 'sticky' and therefore less able to attach to and invade other tissue.The protein, known as S100PBP, does this by suppressing a second protein called cathepsin Z. The research ...

Gene fusion mechanisms offer new clues to origin of pediatric brain tumors

10-Mar-2011 - A detailed analysis of gene fusions present at high frequency in the most common pediatric brain tumors has been performed for the first time in a study published in Genome Research, shedding new light on how these genomic rearrangements form in the early stages of cancer. Genomic rearrangements, ...

Dolphin and bat DNA on the same wavelength

A new study has shown that echolocation evolved separately, but through the same genetic changes, in both dolphins and bats

27-Jan-2010 - Scientists at Queen Mary, University of London have shown that the remarkable ability is shared by these very different animals at a much deeper level than anyone previously realised – all the way down to the molecular level. Writing in Current Biology , they describe how dolphins and bats have ...

Scientists reveal changes to embryonic stem cells caused by Down syndrome

08-Sep-2008 - Scientists investigating the mechanisms of Down Syndrome (DS) have revealed the earliest developmental changes in embryonic stem cells caused by an extra copy of human chromosome 21 – the aberrant inheritance of which results in the condition. Their study is published in the American Journal of ...