NovogeneAIT Singapore and the Genome Institute of Singapore forge Public-Private Partnership

Establishing whole genome sequencing centre in Singapore

08-Dec-2016 - Novogene, a commercial provider of genomic services and solutions with cutting edge next-generation sequencing and bioinformatics expertise; AITbiotech Pte Ltd, a Singapore biotechnology company; and the Genome Institute of Singapore (GIS) announced today that NovogeneAIT Genomics Singapore ...

Singapore Scientists Discover New RNA Processing Pathway Important in Human Embryonic Stem Cells

12-Sep-2013 - Scientists at A*STAR's Genome Institute of Singapore (GIS), in collaboration with their counterparts from Canada, Hong Kong and US, have discovered a protein mediator SON plays a critical role in the health and proper functioning of human embryonic stem cells (hESCs). This finding was reported in ...

Groundbreaking Discovery of the Cellular Origin of Cervical Cancer

14-Jun-2012 - A team of scientists from A*STAR's Institute of Medical Biology (IMB) and Genome Institute of Singapore (GIS) together with clinicians from Boston's Brigham and Women's Hospital (BWH) have identified a unique set of cells in the cervix that are the cause of human papillomaviruses (HPV) related ...

Genetic differences that make some people susceptible to meningitis revealed in major new study

10-Aug-2010 - Genetic differences that make some people susceptible to developing meningococcal meningitis and septicaemia, and others naturally immune, are revealed in a new study of over 6,000 people, published in Nature Genetics . The research, led by Imperial College London and the Genome Institute of ...

Scientists find genes associated with throat cancer through study of over 10,000 subjects

Genome Institute of Singapore and Sun Yat-Sen University Cancer Centre identify 3 new susceptibility genes in genome-wide association study of nasopharyngeal carcinoma

01-Jun-2010 - Scientists from Singapore, China and USA have identified three new susceptibility genes in a genome-wide association study of nasopharyngeal carcinoma (NPC). The study, led by the Genome Institute of Singapore (GIS) and the Sun Yat-Sen University Cancer Centre, identified genetic risk factors of ...

Gene that improves quality of reprogrammed stem cells identified by Singapore scientists

Provides 'a better inkling of what we might aim for before differentiating iPS cells to clinically useful cell types'

10-Feb-2010 - In Nature, scientists at the Genome Institute of Singapore (GIS), report that a genetic molecule, called Tbx3, which is crucial for many aspects of early developmental processes in mammals, significantly improves the quality of stem cells that have been reprogrammed from differentiated cells. ...

Scientists Map Epigenome of Human Stem Cells During Development

Billions of Data Points Provide Big Picture of “Human Epigenome” During Critical Developmental Window

04-Feb-2010 - Scientists at The Genome Institute of Singapore (GIS) and The Scripps Research Institute (TSRI) led an international effort to build a map that shows in detail how the human genome is modified during embryonic development. This detailed mapping is a significant move towards the success of ...

First 'genetic map' of Han Chinese may aid search for disease susceptibility genes

Genome Institute of Singapore researchers compiled map based on genome-wide variations of 6,000 samples

30-Nov-2009 - The first genetic historical map of the Han Chinese, the largest ethnic population in the world, as they migrated from south to north over evolutionary time, was published by the American Journal of Human Genetics by scientists at the Genome Institute of Singapore (GIS). Based on genome-wide ...

Whole genome study reveals clues to solving the mystery behind Kawasaki disease

12-Jan-2009 - A study looking at the entire human genome has identified new genes that appear to be involved in making some children more susceptible to Kawasaki disease, according to a new international study published in PLoS Genetics . The research team, from The University of Western Australia, the Genome ...