10,000 times faster than traditional methods

New computational framework discovers experimental designs in microscopy

12-Dec-2024 - For human researchers, it takes many years of work to discover new super-resolution microscopy techniques. The number of possible optical configurations of a microscope — for example, where to place mirrors or lenses — is enormous. Researchers at the Max Planck Institute for the Science of Light ...

Scientists adapt astronomy method to unblur microscopy images

New method to generate clearer images of thick biological samples

14-Jun-2024 - Astronomers figured out long ago how to make the images their telescopes capture of far-away galaxies clearer and sharper. By using techniques that measure how light is distorted by the atmosphere, they can apply corrections to cancel out aberrations. Microscopists have been adapting these ...

When low batteries are a good thing

27-Jun-2018 - Every day the human gut works on a fine-tuned balance that ensures the retention of essential nutrients while it prevents the entrance of potential armful microbes. Contributing to this surveillance system is a specialised group of immune cells that are held back due to unknown reasons although ...

Stagediving with biomolecules improves optical microscopy

03-May-2018 - Physicists from Dresden and Würzburg have developed a novel method for optical microscopy. Using biological motors and single quantum dots, they acquire ultra-high-resolution images. The resolution of conventional optical microscopy is limited by the fundamental physical principle of diffraction ...

Clever use of mirrors boosts performance of light-sheet microscope

21-Nov-2017 - Using a simple "mirror trick" and not-so-simple computational analysis, scientists affiliated with the Marine Biological Laboratory (MBL) have considerably improved the speed, efficiency, and resolution of a light-sheet microscope, with broad applications for enhanced imaging of live cells and ...

Background suppression for super-resolution light microscopy

01-Feb-2017 - Optical microscopy is applied widely in the life sciences sector. Among others, it is used to minimally invasively examine living cells. Resolution of conventional light microscopy, however, is limited to half the wavelength of light, i.e. about 200 nm, such that finest cellular structures are ...

Crystal clear imaging

Infrared brings to light nanoscale molecular arrangement

17-Oct-2016 - Detailing the molecular makeup of materials -- from solar cells to organic light-emitting diodes (LEDs) and transistors, and medically important proteins -- is not always a crystal-clear process. To understand how materials work at these microscopic scales, and to better design materials to ...