PolyTherics expands collaboration with a top five pharmaceutical company
PolyPEG™ is a patented polymer designed to extend the half-life in the body of therapeutic proteins to which it is conjugated. It consists of poly(ethylene) glycol (PEG) ‘teeth’ along a polymer backbone to create a comb-shaped format. The format of PolyPEG™ provides a conjugated protein with a lower viscosity than would generally be possible with an equivalent sized linear PEG. This is particularly useful when a protein has to be administered at high concentration and can enable the use of standard gauge needles for injection.
Under the terms of the collaboration, the properties of several different proteins will be evaluated following conjugation to a range of PolyPEG® polymers of different molecular architectures. The evaluations will include in vitro binding and activity assays with proteins targeted to a number of disease areas. Selected PolyPEG® protein conjugates will also be evaluated in imaging and pharmacokinetic studies.
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Topic world biopharmaceutical manufacturing
Biopharmaceutical production plays a crucial role in the development and manufacture of biologics, which are essential for the treatment of various serious diseases. Various key technologies and processes of the modern biopharmaceutical industry are used, such as cell cultures, fermentation processes and the purification of biological substances, which are necessary for the production of vaccines, monoclonal antibodies and other biological drugs.
Topic world biopharmaceutical manufacturing
Biopharmaceutical production plays a crucial role in the development and manufacture of biologics, which are essential for the treatment of various serious diseases. Various key technologies and processes of the modern biopharmaceutical industry are used, such as cell cultures, fermentation processes and the purification of biological substances, which are necessary for the production of vaccines, monoclonal antibodies and other biological drugs.