Influenza

Companies Influenza

Atriva Therapeutics GmbH, Germany

ATRIVA aims to develop new antiviral therapies against different respiratory viral infections. Founded in 2015, ATRIVA attracted seasoned experts in virology and drug development to form a unique venture targeting the fast and successful validation of a novel approach to fight infectious diseases In more

News Influenza

• Approved medications – new role in combating infections?
  

  Influenza A viruses periodically cause severe influenza epidemics. Due to their genetic variability, new subtypes can emerge that are no longer covered by seasonal influenza vaccines. Looking for an effective treatment of such serious influenza infections, researchers of the Paul-Ehrlich-Institut ha more

• Snapshots of the flu virus replication machine in action
  

  Researchers from EMBL Grenoble have, for the first time, observed different functional states of the influenza virus polymerase as it is actively transcribing. These results, published in Nature Structural & Molecular Biology, provide valuable information for the next generation of anti-influenza dr more

• Virulence factor of the influenza A virus mapped in real-time
  

  The influenza A viruses, which have instigated deadly pandemics in the past, still remain a major global public health problem until today. Molecules known as virulence factors are produced by bacteria, viruses, and fungi to help them to infect host cells. One of virulence factors found in the influ more

Videos Influenza

How can structural biology help to fight flu?

This short video explains how structural biology can be used to help fight influenza. The clip, which was developed by ELLS in collaboration with EMBL Grenoble scientists working on the EU-funded Flupharm project, is a great tool to introduce students to the topics of influenza, infectious disea ... more

Publications Influenza

• Differentiated human airway organoids to assess infectivity of emerging influenza virus [Microbiology]

  Influenza virus infection represents a major threat to public health worldwide. There is no biologically relevant, reproducible, and readily available in vitro model for predicting the infectivity of influenza viruses in humans. Based on the long-term expanding 3D human airway organoids, we develope more

• Forecasting demand for maternal influenza immunization in low- and lower-middle-income countries

  by Frédéric Debellut, Nathaniel Hendrix, Justin R. Ortiz, Philipp Lambach, Kathleen M. Neuzil, Niranjan Bhat, Clint Pecenka Immunization of pregnant women against seasonal influenza remains limited in low- and lower-middle-income countries despite being recommended by the World Health Organizatio more

• Viruses, Vol. 10, Pages 339: Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus

  Viruses, Vol. 10, Pages 339: Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus Viruses doi: 10.3390/v10070339 Authors: Jana Pokorná Petr Pachl Elena Karlukova Jakub Hejdánek Pavlína Řezáčová Aleš Ma more