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Fixed Dose Procedure
Additional recommended knowledge
FDP uses about 10 to 20 animals to find the dose producing toxicity signs but not death, and from there predicts the lethal dose. LD50 ("lethal dose 50%") uses about 60 to 80 animals to find a dose killing 50% of animals within a given time. FDP sometimes requires retesting using slightly higher or lower doses.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Fixed_Dose_Procedure". A list of authors is available in Wikipedia.|