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David Baker (biochemist)
David Baker is an American biochemist and computational biologist who studies methods to predict the three-dimensional structures of proteins. He is a faculty member in the Department of Biochemistry at the University of Washington in Seattle, Washington.
Additional recommended knowledge
The Baker laboratory developed the Rosetta algorithm for ab initio protein structure prediction, which has been extended to a distributed computing project called Rosetta@Home. The project aims to produce structural models for protein complexes as well as individual polypeptide chains. The Baker group participates regularly and is recognized for expertise in the CASP structure prediction experiment using ab initio methods, including both manually assisted and automated variants of the Rosetta protocol.
Members of the Baker group are also active in the field of protein design; they are recognized as the first group to have designed a protein, known as Top7, with an entirely novel fold.
Baker did his graduate work in biochemistry at the University of California, Berkeley in the laboratory of Randy Schekman, where he worked predominantly on protein transport and trafficking in yeast. Although now known best for their computational work, the Baker laboratory currently maintains an active experimental biochemistry group.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "David_Baker_(biochemist)". A list of authors is available in Wikipedia.|