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4-HO-DET



4-HO-DET
Systematic (IUPAC) name
3-(2-diethylaminoethyl)-1H-indol-4-ol
Identifiers
CAS number 22204-89-3
ATC code  ?
PubChem  ?
Chemical data
Formula C14H20N2O 
Mol. mass 232.32 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
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Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

4-HO-DET, also known as 4-hydroxy-diethyl-tryptamine, CZ-74, or ethocin, is a hallucinogenic drug and psychedelic compound of moderate duration. 4-HO-DET is a substituted tryptamine, structurally related to psilocin and 4-HO-DIPT.

Additional recommended knowledge

Contents

Analogs

The acetic acid ester of 4-HO-DET is known as 4-AcO-DET or ethacetin. The phosphoric acid ester of 4-HO-DET is known as 4-phosphoryloxy-DET, CEY-19, or ethocybin.

History

4-HO-DET received the lab code CZ-74 in the late 1950s by the inventors of the substance, Albert Hofmann and Franz Troxler. The substance was used together with its phosporyloxy-analog CEY-19 in human clinical trials in the 1960s by the German researchers Hanscarl Leuner and G. Baer.

Dosage

10-25mg is the usual oral dosage for 4-HO-DET, while the acetate and phosphate esters are said to require a slightly higher dosage.

Effects

Ethocin produces entheogenic effects similar to LSD and psilocybin. Some users have reported unpleasant anxiety and stimulation with this drug, while other accounts label the experience as being much milder than LSD or psilocybin.

See also

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "4-HO-DET". A list of authors is available in Wikipedia.
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