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GKM (Gesellschaft für Therapieforschung mbH) is an independent, family-owned contract research organization (CRO). GKM provides a comprehensive portfolio of CRO services for the pharmaceutical industry, manufacturers of medical devices and academia. Founded in 1981, GKM is headquartered in Munich, more
Sciomics GmbH was founded in the spring of 2013 as a spin-off company of the German Cancer Research Center (DKFZ) by Dr. Christoph Schröder and Dr. Jörg Hoheisel. Since 2003, our team has gained experience with production and application of antibody microarrays as a tool for analysing complex protei more
A new protein analysis tool developed at the University at Buffalo could vastly increase the speed and precision with which disease and drug effects are analyzed. The groundbreaking tool, called IonStar, is the first to provide near-perfect accuracy when quantifying and comparing the abundance of pr more
Cancer drugs activated by light, minimizing toxic side-effects, are a step closer thanks to new research from University of Warwick and Monash University through the Monash Warwick Alliance Platinum-based chemotherapy drug candidate kills cancer cells in specific targeted areas, and totally inactive more
Scientists from King's College London have found a way to boost the immune system to help it fight back against cancer. The breakthrough involves the first ever use of a combination of chemotherapy and a drug being trialled as a treatment for neonatal jaundice, that together help kick start the body more
The Nobel Assembly awarded this year's Nobel Prize in Medicine to Elizabeth H. Blackburn, Jack W. Szostak, and Carol W. Greider for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. With their ingenious genetic re more
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Case studies on ultra sensitive bioanalysis of biologics with challenging molecular characteristics and the need for broad assay range are discussed. more
As a consumer, it’s easy to be oblivious to the amount of time, work, and money that goes into the development of a drug. The cost of developing a drug that goes on to gain marketing approval was estimated to be $2,558 million in 2014, and the process can commonly last longer than a decade. Addition more
Today’s graphic looks at science in general, rather than just chemistry. It’s in a similar vein to the Rough Guide to Spotting Bad Science posted last year, but this time looking at the hierarchy of different types of scientific evidence. You might think science is science, but some evidence is rank more
We invite you to attend the 7th Cancer Therapeutics & Partnering Summit, to be held on August 28-29, 2018 in San Diego, CA. This summit includes three tracks focused on both the research, and business perspectives in oncology. This summit will continue to be a premier event for translational resear
Course "Introduction to Adaptive Design for Clinical Trials" has been pre-approved by RAPS as eligible for up to 12 credits towards a participant's RAC recertification upon full completion. This 2-day seminar includes an overview of Adaptive Design, and an emphasis in group sequential design, sample
Tumor heterogeneity is a major hurdle for cancer treatment success. To effectively enroll patients in clinical trials, the identification of predictive biomarkers at the preclinical stage is crucial. The use of patient-derived xenograft (PDX) tumor models facilitates the identification of biomarkers
ITG is a subsidiary of ITM Isotopen Technologien München AG, a privately held group of companies dedicated to the development, production and global supply of innovative diagnostic and therapeutic radionuclides and radiopharmaceuticals. We are developing a proprietary portfolio and growing pipeline more
Viruses, Vol. 10, Pages 351: Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy Viruses doi: 10.3390/v10070351 Authors: Frank Oechslin Bacteriophage (phage) therapy, i.e., the use of viruses that infect bacteria as antimicrobial agents, is a promising alte more
In the fight against antibiotic-resistant infections, a decades-old approach based on bacteria-slaying viruses called phages has been sidelined by technical hurdles, dogged by regulatory confusion, and largely ignored by drug developers in the West. But 2 years ago, researchers at the University of more
Antibiotic development is frequently plagued by the rapid emergence of drug resistance. However, assessing the risk of resistance development in the preclinical stage is difficult. By building on multiplex automated genome engineering, we developed a method that enables precise mutagenesis of multip more
Introduction GlobalData's clinical trial report, “Psoriasis Global Clinical Trials Review, H1, 2012" provides data on the Psoriasis clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Psoriasis. It includes an overview of the trial number more
Introduction GlobalData's clinical trial report, “Male Hypogonadism Global Clinical Trials Review, H1, 2012" provides data on the Male Hypogonadism clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Male Hypogonadism. It includes an overv more
Introduction GlobalData's clinical trial report, “Anal Fissure Global Clinical Trials Review, H1, 2012" provides data on the Anal Fissure clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Anal Fissure. It includes an overview of the tri more
AIDS Clinical Trials Group The AIDS Clinical Trials Group (ACTG) is the largest HIV clinical trials organization in the world, playing a major role in setting standards of care for HIV infection and opportunistic diseases related to HIV and AID ... more
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