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GKM (Gesellschaft für Therapieforschung mbH) is an independent, family-owned contract research organization (CRO). GKM provides a comprehensive portfolio of CRO services for the pharmaceutical industry, manufacturers of medical devices and academia. Founded in 1981, GKM is headquartered in Munich, more
We at Inamed believe that being proactive and flexible, is key to success in meeting our clients’ needs. Having established an environment that fosters this approach with our teams, we believe people are our greatest asset and understand that best performances come from individuals who know they are more
Sciomics GmbH was founded in the spring of 2013 as a spin-off company of the German Cancer Research Center (DKFZ) by Dr. Christoph Schröder and Dr. Jörg Hoheisel. Since 2003, our team has gained experience with production and application of antibody microarrays as a tool for analysing complex protei more
QIAGEN N.V. announced it has entered into an agreement to acquire N-of-One, Inc., a privately-held U.S. molecular decision support company and pioneer in clinical interpretation services for complex genomic data. The addition of N-of-One will enable QIAGEN to significantly expand its decision-suppor more
Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia (MMA), a serious genomic disorder. Based on this finding, medical teams treating patients with MMA more
In an article Medical University of South Carolina investigators report that a new compound enhances the efficacy of proteasome inhibitors (PIs), the standard-of-care for the treatment of multiple myeloma (MM), in cell culture and in preclinical models. The efficacy and safety of the novel combinati more
Case studies on ultra sensitive bioanalysis of biologics with challenging molecular characteristics and the need for broad assay range are discussed. more
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
The Nobel Assembly awarded this year's Nobel Prize in Medicine to Elizabeth H. Blackburn, Jack W. Szostak, and Carol W. Greider for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. With their ingenious genetic re more
As a consumer, it’s easy to be oblivious to the amount of time, work, and money that goes into the development of a drug. The cost of developing a drug that goes on to gain marketing approval was estimated to be $2,558 million in 2014, and the process can commonly last longer than a decade. Addition more
Today’s graphic looks at science in general, rather than just chemistry. It’s in a similar vein to the Rough Guide to Spotting Bad Science posted last year, but this time looking at the hierarchy of different types of scientific evidence. You might think science is science, but some evidence is rank more
Viruses, Vol. 10, Pages 351: Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy Viruses doi: 10.3390/v10070351 Authors: Frank Oechslin Bacteriophage (phage) therapy, i.e., the use of viruses that infect bacteria as antimicrobial agents, is a promising alte more
In the fight against antibiotic-resistant infections, a decades-old approach based on bacteria-slaying viruses called phages has been sidelined by technical hurdles, dogged by regulatory confusion, and largely ignored by drug developers in the West. But 2 years ago, researchers at the University of more
Antibiotic development is frequently plagued by the rapid emergence of drug resistance. However, assessing the risk of resistance development in the preclinical stage is difficult. By building on multiplex automated genome engineering, we developed a method that enables precise mutagenesis of multip more
AIDS Clinical Trials Group The AIDS Clinical Trials Group (ACTG) is the largest HIV clinical trials organization in the world, playing a major role in setting standards of care for HIV infection and opportunistic diseases related to HIV and AID ... more
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