Chagas' disease (also called American trypanosomiasis) is a human tropical parasitic disease which occurs in the Americas , particularly in South America . Its pathogen ic agent is a flagellate protozoa n named Trypanosoma cruzi , which is transmitted to humans and other mammal more
In biology , evolution is a change in the inherited traits of a population from one generation to the next. These traits are the expression of gene s that are copied and passed on to offspring during reproduction . Mutation s in these genes can produce new or altered traits, res more
Bupropion (INN ; previously known as amfebutamone, Wellbutrin, Zyban) is an atypical antidepressant that acts as a norepinephrine and dopamine reuptake inhibitor , and nicotinic antagonist . Bupropion belongs to the chemical class of aminoketones and is similar in structure to the stim more
Enzyme inhibitor protease in a complex with the protease inhibitor ritonavir . The structure of the protease is shown by the red, blue and yellow ribbons. The inhibitor is shown as the smaller ball-and-stick structure near the centre. Created from PDB 1HXW .
Enzyme inhibitors are molecule s that more
Cyclol , mainly because it eliminates the resonance stabilization of the peptide bond . This reaction was the basis of Dorothy Wrinch's cyclol model of proteins.
The cyclol hypothesis is the first structural model of a folded , globular protein . The same studies appeared to show that the mo more