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Bioanalytical Support in the Development of Biologics
The Need for Sensitivity combined with broad Assay Range – Case Studies
08-Feb-2016
Case studies on ultra sensitive bioanalysis of biologics with challenging molecular characteristics and the need for broad assay range are discussed.
Immunoassay support for clinical PK assessment where ELISA fails
Imperacer®: Advantages in high sensitivity and dilution tolerance for challenging PK support
20-Apr-2015
Case studies on ultra sensitive bioanalysis of biologics with challenging molecular characteristics, like toxins or fusion-proteins are discussed
Ultra-sensitive Biomarker Quantification in Microsampling Support
New perspectives in analyte quantification by fine-tuning between sensitivity and sample consumption
20-Feb-2015
Looking for Biomarker quantification in microsampling support? Imperacer® enables target detection in low pg/ml range with lowest sample consumption.
RealTime ready RT-qPCR Assay Development and Qualification
01-Jun-2011
On the RealTime ready Configurator, we offer function tested human, mouse, and rat qPCR assays for gene expression quantification based on the unique Universal ProbeLibrary technology (UPL). The Universal ProbeLibrary is a set of short hydrolysis pro
RealTime ready qPCR Assay Design and Configuration Portal Content
01-Jun-2011
The gene and transcript annotational content of the RealTime ready Configurator offers a combined view of three of the main gene annotation authorities. The positional information of the lab-tested RealTime ready assays regarding transcript or exon c
Application of the Amplifluor® SNPs Genotyping System using a FLUOstar OPTIMA microplate reader
16-Jun-2010
The detection of SNPs (single nucleotide polymorphisms) is an important tool for researchers in order to find mutations in DNA sequences. In this application note we describe a homogeneous fluorescence assay based on PCR. The Amplifluor® S
High-Throughput Cardiac Gene Expression Analysis Using the Universal ProbeLibrary and the Novel LightCycler® 1536 Real-Time PCR System
25-Jan-2010
Although congenital heart malformations are the most common birth defects in humans, the underlying pathomechanisms remain widely unknown. Through linkage analyzes and candidate-gene approaches, several gene mutations causing congenital heart defect
MagNA Pure 96 Cellular RNA Kits: RNA Isolation on the Fast Lane
18-Jan-2010
Advancements in high-throughput gene expression analysis have set a new demand for automated isolation of cellular RNA from high sample numbers in parallel. The availability of the innovative MagNA Pure 96 System together with dedicated kits, protoco
The New MagNA Pure 96 DNA and Viral NA Kits: Maximal Speed Combined with High Recovery
18-Jan-2010
The MagNA Pure 96 System is a brand-new system recently introduced to the market: it is a fully automated, ultra-fast system for high-throughput isolation of high- quality nucleic acids from various sample types that can handle sample volumes of up t
Major Histocompatibility Complex Genotyping with Massively Parallel Pyrosequencing
04-Jan-2010
Macaques provide essential preclinical models for infectious disease, vaccine, biodefense, and transplantation research. Unfortunately, they also have the most complex MHC genetics of any primate species described to date, and existing methods for MH
