Contamination-Free and Precise Pipetting of Blood and Plasma

Reliable exclusion of sample carry-over and cross-contamination during pipetting of blood and plasma with positive displacement pipettes

Blood and plasma contain proteins that can lead to foaming during pipetting. This makes it difficult to pipette blood and plasma accurately and contamination-free. Blood is also a vis-cous suspension and may be dangerous. With a positive displacement pipette, the risk of contamination from the sample to the pipette and user is reduced and the absence of the air cushion does not affect the accuracy of the pipette due to the physical properties of the sample (e.g. viscosity and temperature). Disposable Capillary Pistons are the only way to eliminate residual sample carry-over, aero-sol contamination, and cross-contamination when pipetting liquids like blood or plasma. With the disposable piston located inside the capillary tip, your pipette, your sample and yourself are protected against contamination.


This white paper shows how blood and plasma can be pipetted accurately and without con-tamination by comparing positive displacement and air displacement pipetting.

The following questions will be answered:

  • What problems often occur when pipetting plasma and blood?
  • How does a positive displacement pipette work?
  • What are the advantages of the direct displacement pipette?

Facts, background information, dossiers
  • blood
  • positive-displaceme…
  • air-displacement pipettes
More about Gilson
  • White papers

    Improve pipetting of Viscous Liquids in Pharmaceutical Formulations

    Whilst commonly used air displacement pipettes are suited for most liquid dispensing applications, the viscosity of liquids lead to incorrect sample delivery more

    Contamination-Free and Precise Pipetting of Blood and Plasma

    Blood and plasma contain proteins that can lead to foaming during pipetting. This makes it difficult to pipette accurately and without contamination more

  • Companies

    Agilent Technologies Sales & Services GmbH & Co. KG

    Agilent Technologies Inc. (NYSE: A) is a global leader in life sciences, diagnostics and applied chemical markets. Now in its 20th year as an independent company delivering insight and innovation toward improving the quality of life, Agilent instruments, software, services, solutions and ... more

    Analytik Jena GmbH

    Analytik Jena is a leading provider of high-end analytical measuring technology, of instruments and products in the fields of biotechnology and molecular diagnostics, as well as of high quality liquid handling and automation technologies. Its portfolio includes traditional analytical techno ... more

    Pall GmbH

    The life sciences industry is both driven and united by its need for speed to market, product reliability and economics. Pall’s leading edge filtration, separation and purification technologies and services play an essential and pivotal role in this industry’s ability to achieve these goals ... more