GenScript
Discovery of a druggable pocket in the SARS-CoV-2 Spike: A new avenue to defeat COVID-19
Key to SARS-CoV-2 therapeutic development is unraveling the mechanisms driving high infectivity. SARS-CoV-2 is decorated by multiple copies of a glycoprotein,called Spike, which is key to infectivity. Using cryo-electron microscopy, we discovered a potentially druggable pocket within the SARS-CoV-2 Spike. This provides a structural link between COVID-19 pathology and the virus itself, setting the stage for developing new therapeutic intervention.
Prof. Imre Berger
Founding Director Max Planck Bristol Centre University of Bristol UK
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Prof. Imre Berger
Discovery of a druggable pocket in the SARS-CoV-2 Spike: A new avenue to defeat COVID-19
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