€ 1 Million Research Grant Awarded for the First Time
Merck awarded a grant known as the Future Insight Prize for the first time. Pardis Sabeti, Harvard University and the Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA, and James Crowe, Vanderbilt University Medical Center, Nashville, Tennessee, USA, were recognized for thei ... more
Evolution of a deadly virus
Infections caused by the mosquito-borne eastern equine encephalitis virus (EEEV) are severe and have high mortality rates for horses - 90 percent - and humans - 33 percent, with significant brain damage in most human survivors.
Florida has been hypothesized to be the source of EEEV epidemic ... more
New view of the heartbeat
The human cardiac voltage-gated sodium channel (Nav1.5) plays a critical role in maintaining regular heartbeats. Mutations in Nav1.5 cause life-threatening heart rhythm disorders (arrhythmias).
Nav1.5 is sensitive to the calcium-ion sensor protein calmodulin (CaM); however, the exact mechan ... more