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News Transposons

  • Harnessing jumping genes to advance gene-therapy cancer treatment

    In an effort to optimize the Sleeping Beauty system, the MDCell – Helmholtz Innovation Lab is extending its collaboration with PlasmidFactory. If you want to modify a human body’s immune cells – for example by giving them new vitality to fight a tumor or stop an autoimmune disease – you need safe an more

  • EMBL spins the Sleeping Beauty transposase

    EMBL scientists have developed a new variant of the Sleeping Beauty transposase. It has dramatically improved biochemical features, including enhanced stability and intrinsic cell penetrating properties. This transposase can be used for genome engineering of stem cells and therapeutic T cells. As su more

  • Antibiotic resistances spread faster than so far thought

    By studying fish raised in aquaculture, researchers from the Helmholtz Zentrum München, the University of Copenhagen and the University of Campinas in Brazil have shed new light on the mechanisms by which antibiotic resistance genes are transferred between bacteria. According to the study published more

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Videos Transposons

Real-time observation of transposon activity in living cells

Sections taken from the top to the bottom of a large E. coli colony (~1 mm diameter, ~1 billion E. coli) where the cells are carrying a “wildtype” version of the transposable element reveals complex spatial patterns as a result of transposable element mutations. Video courtesy of T.E. Kuhlman, U ... more

Publications Transposons

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Transposon Transposons are sequences of DNA that can move around to different positions within the genome of a single cell , a process called transposition. In the process, they can cause mutation s and change the amount of DNA in the genome. ... more


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