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RNA Interference

The technique regularly makes the science headlines, and drugs it is based on have reached the clinical development stage – RNA interference is on everyone’s lips, thanks to enabling a comparatively straightforward technique of silencing genes. The market volume of RNAi products and services is predicted to reach four thousand million US dollars by 2017, with siRNA synthesis seen as having the greatest growth potential.

Companies RNA Interference


SIRION Biotech is Europe's leading commercial supplier of viral vectors used for genetic cell modelling, gene target validation and gene therapy- and vaccination studies. Since its foundation in 2007, SIRION’s mission has been to change the paradigm for viral vector supplies. It has the ability to more

News RNA Interference

  • Unusual soybean coloration sheds a light on gene silencing

    Today's soybeans are typically golden yellow, with a tiny blackish mark where they attach to the pod. In a field of millions of beans, nearly all of them will have this look. Occasionally, however, a bean will turn up half-black, with a saddle pattern similar to a black-eyed pea. "The yellow color i more

  • Lipid nanoparticles for gene therapy

    Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy. Until now, viral systems have been the most effective method for delivering genetic matter but they pose significant safety problems. "Non-viral vectors, including SLNs and NLCs more

  • CSIRO maintains foundational patent for RNAi gene silencing technology after European opposition

    The Commonwealth Scientific and Industrial Research Organisation (CSIRO), has successfully defended its foundational patent in Europe for RNA interference (RNAi) gene silencing technology. RNAi technology is a powerful method that is widely used as a research tool to test the function of genes and i more

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White papers RNA Interference

Events RNA Interference


RNAi and CRISPR/Cas9: Revolutionizing Drug Discovery

In drug discovery, the key to success often depends on the models used. This webinar discusses how Charles River’s model creation partner, Mirimus, has leveraged RNA interference (RNAi) and CRISPR/Cas9 technologies to enhance the speed and precision of new genetically engineered mouse models. This r

Publications RNA Interference

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Market studies RNA Interference

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RNA interference

RNA interference trims double stranded RNA, to form small interfering RNA or microRNA . These processed RNAs are incorporated into the RNA-induced silencing complex (RISC), which targets messenger RNA to prevent translation . RNA interferen ... more


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