Growing brain cancer in a dish
Brain tumors are among the most aggressive and deadly cancers and a leading cause of cancer-related death in children and young adults. Glioblastoma is a particularly aggressive form of brain tumor that is characterized by a very rapid tumor growth of glia cells – the most abundant cell ty ... more
Scientists characterise cancer genes using ground-breaking new method
In a paper in the journal “Science”, researchers from the Vienna BioCenter combine cutting-edge technologies to decipher regulatory functions of important cancer genes.
Key to this success is an innovative method called “SLAMseq”, which allows the direct detection of sudden changes in gene ... more
Haplobank – a biobank of reversible mutant embryonic stem cells
The Penninger lab at the IMBA developed a biobank of revertible, mutant embryonic stem cells. This cell bank – called Haplobank - contains over 100,000 mutated, conditional mouse embryonic stem cell lines, targeting about 70% of the protein-coding genome.
Genetic screens have revolutionized ... more