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Chromatography Resins: MabSelect

Bring your Protein A purification to the next level

Cytiva Europe GmbH

High Alkaline stability

Optimized for high capacity and throughput

High purification factor due to low nonspecific protein binding

MabSelect a BioProcess proteinA resin for capturing monoclonal antibodies from large sample volume

The MabSelect™ family comprises MabSelect, MabSelect Xtra™, MabSelect SuRe™ and MabSelect SuRe LX. MabSelect Xtra is based on high-flow agarose base matrix with slightly increased porosity and decreased particle size, resulting in higher dynamic binding capacity and higher capacity for many Fc-fusion proteins.

MabSelect SuRe is based on an alkali-stabilized rProtein A-based ligand that provides greater stability than conventional rProtein A-based resins, allowing extended use of 0.1–0.5 M NaOH for cleaning in place. MabSelect SuRe LX gives even higher binding capacity at longer residence time. The latest addition to the MabSelect resin family is MabSelect PrismA™, an affinity chromatography resin that has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein A-derived ligand. This allows future demands in mAb purification to be met, including processing of many bispecific antibodies. MabSelect PrismA delivers enhanced dynamic binding capacity and excellent alkaline stability enabling efficient cleaning and sanitization using 0.5–1.0 M NaOH

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Evolution of Sepharose™ based resins towards modern Capto™ and MabSelect™ based resins

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mAb Toolbox - cytivalifesciences.com/en/gb/solutions/bioprocessing/knowledge-center/get-started-with-mabselect-prisma-protein-a-resin

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MabSelect™ PrismA offers improved dynamic binding capacity

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Normalized cost per batch and resin lifetime

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Overview of prepacked formats containing MabSelect PrismA™ resin including Fibro PrismA units, which contain the same PrismA ligand.

Product classification

Applications

Product categories

affinity resins
chromatography gels
Chromatography Resins

Target Industries

Biotechnology
Pharma

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Chromatography Resins: MabSelect

Bring your Protein A purification to the next level

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View topic world

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

20+ products
10+ whitepaper
20+ brochures