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187 Current news about the topic pathology

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Researchers use AI to establish molecular tumor classification and prognosis in patients with colorectal cancer

08-Jul-2019

Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma. A research team from University Hospital Zurich and the University of Oxford have now developed a method to predict the molecular classification of ...

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In the fight against Alzheimer's, Down syndrome may hold vital clues

18-Oct-2018

At first glance, Down syndrome (DS) and Alzheimer's disease (AD), two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the source of which has long been recognized--a triplication of chromosome 21. By contrast, the overwhelming majority of ...

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Principles of limb regeneration in salamanders show link to mammals

01-Oct-2018

Scientists have long argued over which cells enable salamanders to grow back lost limbs. By tracking lineages and characterising individual cells, researchers could now show that connective tissue cells develop stem-cell-like properties and underlie the regeneration of legs. Among all four-legged ...

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Why some people with brain markers of Alzheimer’s have no dementia

22-Aug-2018

A new study from The University of Texas Medical Branch at Galveston has uncovered why some people that have brain markers of Alzheimer’s never develop the classic dementia that others do. Alzheimer’s disease, the most common form of dementia, affects more than 5 million Americans. People ...

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Genes that helps prevent brain disease

18-May-2018

Scientists know that faulty proteins can cause harmful deposits or "aggregates" in neurological disorders such as Alzheimer's and Parkinson's disease. Although the causes of these protein deposits remain a mystery, it is known that abnormal aggregates can result when cells fail to transmit proper ...

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Lack of sleep may be linked to risk factor for Alzheimer's disease

17-Apr-2018

Losing just one night of sleep led to an immediate increase in beta-amyloid, a protein in the brain associated with Alzheimer's disease, according to a small, new study by researchers at the National Institutes of Health. In Alzheimer's disease, beta-amyloid proteins clump together to form ...

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Biomarker helps identify 'window of opportunity' for cancer chemotherapy timing

11-Apr-2018

Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics. Combination therapy using angiogenesis ...

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The largest genome ever

Decoding the Axolotl

26-Jan-2018

A team of researchers led by scientists in Vienna, Dresden and Heidelberg has decoded the entire genetic information of the Mexican salamander axolotl. The axolotl genome, which is the largest genome ever to be sequenced, will be a powerful tool to study the molecular basis for re-growing limbs ...

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A swallowable test to detect pre-cancerous Barrett's esophagus

19-Jan-2018

Investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have developed a simple, swallowable test for early detection of Barrett's esophagus that offers promise for preventing deaths from esophageal adenocarcinoma. Barrett's esophagus ...

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Microscope using UV instead of visible light emerging as diagnostic tool

06-Dec-2017

MUSE image of sebaceous glandA microscope using ultraviolet light to illuminate samples enables pathologists to assess high-resolution images of biopsies and other fresh tissue samples for disease within minutes, without requiring the time-consuming preparation of conventional slides or ...

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