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Insights into healthy aging mechanisms from the roundworm
26-Nov-2018 - Median life expectancy of our society is still increasing which leads us to the question: how can we extend healthy aging? This is being investigated on a molecular level in the model organism Caenorhabditis elegans, a transparent round worm with a size of about 1 mm. It is widely used in ...
03-Aug-2018 - The “Disposable Soma Theory of Aging” suggests that each organism has only limited energy at its disposal. This energy must be distributed between the maintenance of somatic tissue and reproduction. Species confronted with a high extrinsic mortality are more likely to invest their energy in ...
African killifish as model organism
27-Jul-2018 - Nothobranchius furzeri, the African killifish, is the perfect model organism for research into aging processes because of its short lifespan, apparent signs of aging and a sequenced genome. Thus, researchers from the University of Veterinary Medicine Vienna and the Medical University of Vienna ...
Key molecule of aging discovered
22-Jun-2018 - Every cell and every organism ages sooner or later. But why is this so? Scientists at the German Cancer Research Center in Heidelberg have now discovered for the first time a protein that represents a central switching point in the aging process. It controls the life span of an individual - from ...
18-May-2018 - Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts. In a study the researchers show that the approach increased the lifespans of worms and flies, ...
06-Apr-2018 - The genetic basis of lifespan determination is poorly understood. Most research has been done on short-lived animals, and it is unclear if these insights can be transferred to long-lived mammals like humans. By comparing genes of long- and short-lived rodents, researchers from Leibniz Institute ...
Tissues respond very differently to an ageing ameliorating intervention
09-Oct-2017 - In old age a variety of cellular processes decline and the risk to develop age-related diseases such as Alzheimer’s, Parkinson’s or Diabetes increases dramatically. But does ageing affect all organs and tissues in the body in the same way? And should drugs that are developed to improve health in ...
12-Sep-2017 - The programme controls how and when brain genes are expressed at different times in a person's life to perform a range of functions, the study found. Experts say the timing is so precise that they can tell the age of a person by looking at the genes that are expressed in a sample of brain ...
08-Sep-2017 - To understand and control aging is the aspiration of many scientists. Researchers at the Biozentrum of the University of Basel have now discovered that the protein Gcn4 decreases protein synthesis and extends the life of yeast cells. Understanding how individual genes affect lifespan opens new ...
Is it possible to do both?
08-Jun-2017 - Exactly when does old age begin? Which health markers best predict who will live a long and healthy life versus a life spent in poor health? Developing metrics to help answer these questions and to understand the tradeoffs between lifespan and health span is the subject of a recent paper by MDI ...
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