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25-Apr-2017 - Stem cell transplants can save lives, for example in patients with leukemia. However, these treatments are not free of risks. One complication that may occur is graft-versus-host disease (GVHD), basically donor-derived immune cells attacking the recipient’s body. A team at the Technical ...
08-Mar-2017 - Regeneration is an inherent property of life. However, the potential to regenerate differs across species: while fish and amphibians can re-grow appendages such as limbs, tails, and fins, mammals, including humans, cannot restore injured organs to their original shape and function. Therefore, ...
28-Oct-2016 - The presence of various cell types in tumors – cellular heterogeneity – makes treatment challenging, since a therapy may kill one cell type but not affect another. Studying heterogeneous cell populations requires single-cell analysis. Ken Lau , Ph.D., and colleagues previously described a method ...
13-Oct-2016 - Toward the ultimate goal of engineering human tissues and organs that can mimic native function for use in drug screening, disease modeling, and regenerative medicine, a Wyss Institute team led by Core Faculty member Jennifer Lewis, Sc.D., has made another foundational advance using ...
24-Aug-2016 - Researchers at the universities of Basel and Oxford have for the first time identified all genes regulated by the protein Foxn1. The results show that Foxn1 not only plays a crucial role in development of the thymus in the embryo, but it also regulates vital functions in the developed, postnatal ...
24-Jun-2016 - A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the ...
15-Jun-2016 - In the study, USC Stem Cell researcher In Kyoung Mah from the laboratory of Francesca Mariani and colleagues demonstrated Prkci's role in organizing cells into balls and tubes during early embryo and organ formation. In their experiments, the researchers used mouse stem cells to form what are ...
23-Nov-2015 - Champion of regeneration, the freshwater polyp Hydra is capable of reforming a complete individual from any fragment of its body. It is even able to remain alive when all its neurons have disappeared. Researcher the University of Geneva (UNIGE), Switzerland, have discovered how: cells of the ...
Technique produces 'organoids' useful in cancer research, drug screening
02-Sep-2015 - A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural ...
15-Jun-2015 - About 70.000 Women are diagnosed with breast cancer every year in Germany alone. Despite significant progress in the treatment of common types of breast cancer, some aggressive subtypes of the disease are poorly understood and remain incurable. A new experimental model opens new avenues for ...
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