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2,896 Current news about the topic diseasesrss
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New method to improve the diagnosis of genetic diseases
Breaks and rearrangements in the genome can lead to severe diseases, even if all genes remain intact. Hi-C, a method to map the three-dimensional structure of chromosomes, promises more reliable and accurate diagnoses of such defects, but is not used in the clinic yet. A team of researchers at ...
Companies to collaborate on mRNA vaccine and monoclonal antibody research programmes in infectious diseases
GlaxoSmithKline plc and CureVac announced the signing of a strategic collaboration agreement for the research, development, manufacturing and commercialisation of up to five mRNA-based vaccines and monoclonal antibodies (mAbs) targeting infectious disease pathogens. The collaboration complements ...
Belly fat as a source of chronic inflammation
Frailty and immune decline are two main features of old age. Researchers from the University of Bern and the University Hospital Bern now demonstrate in an animal model that these two age-related impairments can be halted and even partially reversed using a novel cell-based therapeutic ...
Ability to eliminate spent proteins influences brain aging and individual life span
Aging is the main risk factor for dementia and Parkinson’s disease. As age progresses, toxic protein aggregates pile up in the brain and impair neuronal function. But why does that happen? An international team of scientists coordinated by the Leibniz Institute on Aging - Fritz Lipmann Institute ...
Launch of Start-up QLi5 Therapeutics
The Lead Discovery Center GmbH (LDC) and the South Korean drug development specialist Qurient have founded QLi5 Therapeutics GmbH, together with their partners, the Max Planck Society (MPG) and Nobel laureate Prof. Huber, emeritus director of the Max Planck Institute for Biochemistry. Dortmund ...
Hitherto unknown molecular function of a specific microRNA preserves integrity of the endothelium and reduces the risk of atherosclerosis
Short RNA molecules known as microRNAs (miRNAs) play a vital role in the regulation of gene expression. Anomalies in miRNAs expression and function have been implicated in pathological processes, such as the development of chronic diseases like atherosclerosis. The regulatory functions of miRNAs ...
A promising but delicate therapeutic target
An interdisciplinary research study of the University of Barcelona identified two potential candidates to treat Alzheimer's disease. These are two marine molecules, meridianine and lignarenone B, able to alter the activity of GSK3B activity, a protein associated with several neurodegenerative ...
How alcohol in moderation has a positive effect on impaired immune reactions
We all know that excessive consumption of alcohol is bad for our health. Moderate quantities of alcohol, however, can be beneficial to our health in some circumstances. In a paper published in Nature, a team of researchers from FAU shows that alcohol modifies the immune system in a very specific ...
Clotting cells are also an important regulator of inflammation
Platelets not only play a key role in blood clotting, but can also significantly intensify inflammatory processes. This is shown by a new study carried out by scientists from the University of Bonn together with colleagues from Sao Paulo (Brazil). In the medium term, the results could open up new ...
Researchers discover new pathomechanism of hereditary diseases in cell condensates
Repeats of individual building blocks within proteins are the cause of many hereditary diseases, but how such repeats actually cause disease is still largely unknown. Researchers in Berlin investigated how repeat elongations lead to the disease synpolydactyly, and have found that the attractive ...