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2,872 Current news about the topic diseases

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The gut may be involved in the development of multiple sclerosis

06-Dec-2019

The gut has long been suspected to play a role in autoimmune disease. A research team has now identified evidence of a potential mechanism. It is incompletely understood which factors in patients with multiple sclerosis (MS) act as a trigger for the immune system to attack the brain and spinal ...

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Small RNAs link immune system and brain cells

Sex-specific processes in schizophrenia and bipolar disorder

13-Nov-2019

Recent studies have found a high genetic similarity of the psychiatric diseases schizophrenia and bipolar disorder, whose disease-specific changes in brain cells show an overlap of more than 70 percent. These changes affect gene expression, i.e., transcription of genes for the purpose of ...

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What and how much we eat might change our internal clocks and hormone responses

08-Nov-2019

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research (DZD) shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course ...

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Evotec and Vifor Pharma form joint venture

07-Nov-2019

Evotec SE and Vifor Pharma announced the launch of a 50:50 joint venture focused on the discovery and development of novel nephrology therapeutics. Vifor Pharma will be benefiting from access to an external R&D capability for the development of its own nephrology pipeline, while Evotec will gain ...

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Measles infections erase immunological memory

04-Nov-2019

Measles infections are not harmless - they can cause disease courses that may be of fatal outcome. Researchers of the Paul-Ehrlich-Institut (PEI) in co-operation with researchers from the UK and the Netherlands have now found out that measles viruses erase part of the immunological memory over ...

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Allergy sufferers are more susceptible to stress and tend to suppress emotions

04-Nov-2019

Do allergic and non-allergic individuals differ in their response to acute stress and in how they handle emotions? A research team led by Lisa Maria Glenk from the interuniversity Messerli Research Institute (a joint institution of Vetmeduni Vienna, MedUni Vienna and the University of Vienna) ...

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Striking a balance: a mechanism to control autoimmunity

09-Oct-2019

B cells are white blood cells that generate antibodies against an almost unlimited number of pathogens, a capacity that is vital for any higher organism. However, establishing a diverse repertoire of pathogen recognition comes at a price, as some B cells will inevitably go wild and turn against ...

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Evotec reaches milestone in integrated drug discovery and development partnership with Aeovian

07-Oct-2019

Evotec SE announced that the Company has reached a milestone in a drug discovery and development partnership with the biopharmaceutical company Aeovian Pharmaceuticals, Inc. Aeovian and Evotec entered into a drug discovery partnership in 2017 to discover and develop new and highly selective ...

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Healthy organelles, healthy cells

02-Oct-2019

It has recently become clear just how important membraneless organelles are for cells. Now biochemists at ETH Zurich have discovered a novel mechanism that regulates the formation of these organelles. This has laid the foundation for more targeted research into diseases such as Alzheimer’s or ...

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Evotec and Takeda enter collaboration agreement to discover clinical candidates across multiple therapeutic areas

24-Sep-2019

Evotec SE announced a strategic, multi-year drug discovery collaboration with Takeda Pharmaceutical Company Limited. Under the collaboration, the parties aim to establish at least five drug discovery programmes with the goal of Evotec delivering clinical candidates for Takeda to pursue into ...

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