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171 Current news about the topic crispr

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Pioneering research projects at the 8th Life Science Pitch Day at the IZB

A total of sixteen teams presented their innovative ideas to almost 50 investors at the Munich start-up center.

18-Jul-2023 - On July 13, 2023, the Munich Innovation and Start-up Center for Biotechnology (IZB) organized the 8th Life Science Pitch Day in cooperation with High-Tech Gründerfonds (HTGF), Leaps by Bayer, and Boehringer Ingelheim, which brought together sixteen biotech start-ups and project teams and almost ...

antibiotics artificial intelligence autoimmune diseases +10
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Researchers visualise activity of CRISPR genetic scissors

New method allows precise observation of gene recognition

14-Jul-2023 - Scientists at Leipzig University, in collaboration with colleagues at Vilnius University in Lithuania, have developed a new method to measure the smallest twists and torques of molecules within milliseconds. The method makes it possible to track the gene recognition of CRISPR-Cas protein ...

CRISPR DNA DNA nanostructures +6
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Gene scissors find target for testicular cancer therapy

Researchers uncover contribution of protein degradation processes to cisplatin resistance in germ cell tumors

21-Apr-2023 - Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options. Researchers at the University Hospital Bonn (UKB) have now been able to elucidate a mechanism underlying cisplatin ...

cancer chemotherapy cisplatin +4
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Alternative glucose breakdown ensures the survival of cancer cells

How cancer cells defy oxidative stress

12-Apr-2023 - A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now shown that with this oxidation, cells switch to an alternative sugar breakdown pathway and can ...

cancer cancer cells cells +6
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Klara – A transparent fish for research on aging

Inactivation of pigmentation using CRISPR/Cas9

21-Mar-2023 - For in vivo studies of internal processes in an organism, body pigmentation is a considerable limitation. To circumvent this, various transparent fish models have already been generated, and are used in cancer research, among other things. In research on aging, however, these fish are rarely ...

animal models CRISPR CRISPR/Cas9 +3
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BRAIN Biotech and TransCode Therapeutics join forces to develop a CRISPR-derived technology platform for cancer treatment

Development of a CRISPR-derived technology platform for cancer treatment

06-Mar-2023 - BRAIN Biotech AG announced the signing of a joint development agreement (JDA) with TransCode Therapeutics, Inc. The objective of the JDA is to co-develop a platform technology that combines a Class 2 CRISPR nuclease, the cell-killing G-dase E, developed by BRAIN Biotech's Akribion Genomics unit ...

cancer CRISPR
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When editing bacteria with CRISPR, less is more

Research team develops approach that increases efficiency of genome editing

13-Feb-2023 - Systematically attenuating DNA targeting activity can achieve CRISPR-driven editing in bacteria, greatly boosting colony counts and even increasing the frequency of precise genome editing. This was shown in a study of the Helmholtz Institute Würzburg (HIRI) in collaboration with the Helmholtz ...

bacteria CRISPR genome editing
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Artificial Intelligence Improves Efficiency of Genome Editing

Long-term goal: repairing hereditary diseases

06-Feb-2023 - Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options. Unintentional errors in the correction of DNA mutations of genetic diseases can thus be reduced. Genome editing technologies offer ...

artificial intelligence CRISPR CRISPR/Cas9 +5
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Avoiding burnout of white blood cells

New ways for more efficient immunotherapies

06-Feb-2023 - A research group funded by the Swiss National Science Foundation has identified a gene that drives T lymphocytes to exhaustion. This opens up new approaches for more effective immunotherapies. A tough battle requires endurance. This is also true for white blood cells as they tackle cancer – or ...

cancer CRISPR CRISPR/Cas9 +3
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Genome Editing Procedures Optimised

Scientists succeed in boosting the efficiency of CRISPR/Cas9 and related methods and modifying initially inaccessible DNA sequences

01-Feb-2023 - In the course of optimising key procedures of genome editing, researchers from the department of Developmental Biology / Physiology at the Centre for Organismal Studies of Heidelberg University have succeeded in substantially improving the efficiency of molecular genetic methods such as ...

CRISPR CRISPR/Cas9 gene mutations +1